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目录产品 » Galectin-9/LGALS9, His, Human
Galectin-9/LGALS9, His, Human

Recombinant Galectin-9/LGALS9, His, Human on SDS-PAGE under reducing conditions, the purity is greater than 95%.

Galectin-9/LGALS9, His, Human

Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Z03654
￥2240

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产品简介
Species Human
Protein Construction
Galectin-9/LGALS9 (Met1-Thr323)
Accession # Q3B8N1-2		 Poly-His
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Expression System Human Cells
Apparent Molecular Weight ~49 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution in 50 mM MOPS, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, 5% Trehalose, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4-7°C and up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles.

图例
  • Galectin-9/LGALS9, His, Human
    • Galectin-9/LGALS9, His, Human

    Recombinant Galectin-9/LGALS9, His, Human on SDS-PAGE under reducing conditions, the purity is greater than 95%.


技术背景
Target Background Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1.
Synonyms Galectin-9; Gal-9; Ecalectin; Tumor Antigen HOM-HD-21; LGALS9

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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