| Species |
Human |
| Protein Construction |
CEACAM-5/CD66e (Pro501-Ala685)
Accession # P06731-1 |
His |
| N-term |
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Biological Activity |
Immobilized CEACAM-5/CD66e (501-685), His, Human (Cat.No.: Z03832) at 2 μg/ml (100μl/Well) on the plate can bind Anti-CEACAM5 Antibody. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
20.89 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
CEACAM5 (Carcinoembryonic antigen-related cell adhesion molecule 5), is also known as CD66e (Cluster of Differentiation 66e). The overproduction of CEACAM5 could enrich for an epithelial gene expression pattern and facilitate tumor outgrowth at metastatic sites. CEACAM5 is often used as a synonym for many types of malignancies, such as colorectal cancer and non-small-cell lung cancer. |
| Synonyms |
CEACAM-5; CD66e; CEA; Meconium antigen 100; Carcinoembryonic; CEACD66e; DKFZp781M2392 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
