| Species |
Human |
| Protein Construction |
CEACAM-6CD66c (Lys35-Gly320)
Accession # P40199 |
His |
Avi |
| N-term |
|
C-term |
|
| Purity |
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC |
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
34.1 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 55-75 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. |
| Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
| Target Background |
CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6), is encoded by the human CEACAM6 gene. It plays a probable role in both cell-cell signaling and cell adhesion, promoting tumor progression, invasion and metastasis. It is upregulated in pancreatic adenocarcinoma, breast cancer and non-small cell lung cancer. |
| Synonyms |
CEACAM6; CD66c; CEAL; NCA; CEA |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
