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Characterization of core oligosaccharide synthesis reveals novel aspects of lipooligosaccharide assembly

Authors: Leah M VanOtterloo, Luis A Macias, Matthew J Powers, Jennifer S Brodbelt, M Stephen Trent

Journal: MBio

PubMed ID: 38349180

Doi: 10.1128/mbio.03013-23

Products & Services: Gene Synthesis

Increasing β-hexosaminidase A activity using genetically modified mesenchymal stem cells

Authors: Alisa A Shaimardanova , Daria S Chulpanova , Valeriya V Solovyeva 1, Shaza S Issa , Aysilu I Mullagulova , Angelina A Titova , Yana O Mukhamedshina , Anna V Timofeeva , Alexander M Aimaletdinov , Islam R Nigmetzyanov , Albert A Rizvanov

Journal: Neural Regen Res .

PubMed ID: 37488869

Doi: 10.4103/1673-5374.375328

Products & Services: Gene Synthesis

TREM2 variants that cause early dementia and increase Alzheimer's disease risk affect gene splicing

Authors: Kostantin Kiianitsa, Maria E Lukes, Brian J Hayes, Julianna Brutman, Paul N Valdmanis, Thomas D Bird, Wendy H Raskind, Olena Korvatska

Journal: Brain

PubMed ID: 38226698

Doi: 10.1093/brain/awae014

Products & Services: Gene Synthesis Mutagenesis Services Plasmid DNA Preparation

Glyoxylate reductase: Definitive identification in human liver mitochondria, its importance for the compartment-specific detoxification of glyoxylate

Authors: Sander F Garrelfs, Serhii Chornyi, Heleen Te Brinke, Jos Ruiter, Jaap Groothoff, Ronald J A Wanders

Journal: J Inherit Metab Dis

PubMed ID: 38200664

Doi: 10.1002/jimd.12711

Products & Services: Gene Synthesis

Stabilization of the Metastable Pre-Fusion Conformation of the SARS-CoV-2 Spike Glycoprotein through N-Linked Glycosylation of the S2 Subunit

Authors: Fuwen Zan, Yao Zhou, Ting Chen , Yahan Chen, Zhixia Mu, Zhaohui Qian , Xiuyuan Ou

Journal: Viruses.

PubMed ID: 38399999

Doi: 10.3390/v16020223

Products & Services: Gene Synthesis

Mining and rational design of psychrophilic catalases using metagenomics and deep learning models

Authors: Shuning Wu, Guoshun Xu, Yongping Su, Huoqing Huang, Xinxin Xu, Yuhong Zhang, Jian Tian, Wei Zhang, Zhiwei Zhang, Bo Liu

Journal: Appl Microbiol Biotechnol

PubMed ID: 38175233

Doi: 10.1007/s00253-023-12926-1

Products & Services: Gene Synthesis

A high catalytic efficiency and chemotolerant formate dehydrogenase from Bacillus simplex

Authors: Rattima Boonkumkrong, Paweenapon Chunthaboon, Pobthum Munkajohnpong, Pratchaya Watthaisong, Panu Pimviriyakul, Somchart Maenpuen, Pimchai Chaiyen, Ruchanok Tinikul

Journal: Biotechnol J

PubMed ID: 38180313

Doi: 10.1002/biot.202300330

Products & Services: Gene Synthesis

Sast1-mediated manifold effects inhibit Plutella xylostella fertility

Authors: Min-Hui Cao, Ming-Min Zou, Li-Li Liu, Shi-Jie Dong, Meng-Qi Huang, Jun-Hao Zheng, Ruo-Nan Li, Jin-Dong Cui, Lu Peng

Journal: Pest Manag Sci

PubMed ID: 38252701

Doi: 10.1002/ps.7966

Products & Services: Gene Synthesis

Nitrated T cell epitope linked vaccine targeting CD47 elicits antitumor immune responses and acts synergistically with vaccine targeting PDL1

Authors: Danni Deng, Guozhi Li, Xuefei Xia, Shuyang Xu, Le Gao, Li Zhang, Wenbing Yao, Hong Tian, Xiangdong Gao

Journal: Int Immunopharmacol

PubMed ID: 38181672

Doi: 10.1016/j.intimp.2023.111374

Products & Services: Gene Synthesis

Glycosylase-based base editors for efficient T-to-G and C-to-G editing in mammalian cells

Authors: Lijun Ye , Dongdong Zhao , Ju Li , Yiran Wang , Bo Li , Yuanzhao Yang , Xueting Hou , Huibin Wang , Zhandong Wei , Xiaoqi Liu , Yaqiu Li, Siwei Li , Yajing Liu , Xueli Zhang , Changhao Bi

Journal: Nat Biotechnol .

PubMed ID: 38168994

Doi: 10.1038/s41587-023-02050-w

Products & Services: Gene Synthesis Gene Synthesis