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Inhibition of chitin deacetylases to attenuate plant fungal diseases

Authors: Lin Liu, Yeqiang Xia, Yingchen Li, Yong Zhou, Xiaofeng Su, Xiaojing Yan, Yan Wang, Wende Liu, Hongmei Cheng, Yuanchao Wang, Qing Yang

Journal: Nat Commun

PubMed ID: 37385996

Doi: 10.1038/s41467-023-39562-7

Products & Services: Gene Synthesis

Structural basis for the binding of DNP and purine nucleotides onto UCP1

Authors: Yunlu Kang, Lei Chen

Journal: Nature

PubMed ID: 37336486

Doi: 10.1038/s41586-023-06332-w

Products & Services: Gene Synthesis

Characterization of the conserved features of the NSE6 subunit of the Physcomitrium patens SMC5/6 complex

Authors: Edit Lelkes , Jitka Jemelková , Marcela Holá , Barbora Štefanovie , Peter Kolesár , Radka Vágnerová , Eva Dvořák Tomaštíková , Ales Pecinka , Karel J Angelis , Jan J Paleček

Journal: Plant J .

PubMed ID: 37191775

Doi: 10.1111/tpj.16282

Products & Services: Gene Synthesis

13C Electron Nuclear Double Resonance Spectroscopy-Guided Molecular Dynamics Computations Reveal the Structure of the Enzyme–Substrate Complex of an Active, N-Linked Glycosylated Lipoxygenase

Authors: Ajay Sharma , Chris Whittington , Mohammed Jabed , S Gage Hill , Anastasiia Kostenko , Tao Yu , Pengfei Li , Peter E Doan , Brian M Hoffman , Adam R Offenbacher

Journal: Biochemistry .

PubMed ID: 37115010

Doi: 10.1021/acs.biochem.3c00119

Products & Services: Gene Synthesis

In-cell kinetic stability is an essential trait in metallo-β-lactamase evolution

Authors: Lisandro J González, Guillermo Bahr, Mariano M González, Robert A Bonomo, Alejandro J Vila

Journal: Nat Chem Biol

PubMed ID: 37188957

Doi: 10.1038/s41589-023-01319-0

Products & Services: Gene Synthesis

Electronegative clusters modulate folding status and RNA binding of unstructured RNA-binding proteins

Authors: Steve Zaharias, Talia Fargason, Rory Greer, Yuhua Song, Jun Zhang

Journal: Protein Sci

PubMed ID: 37060324

Doi: 10.1002/pro.4643

Products & Services: Gene Synthesis

De Novo Computational Design of a Lipase with Hydrolysis Activity towards Middle-Chained Fatty Acid Esters

Authors: Jinsha Huang, Xiaoman Xie, Zhen Zheng, Luona Ye, Pengbo Wang, Li Xu, Ying Wu, Jinyong Yan, Min Yang, Yunjun Yan

Journal: Int J Mol Sci

PubMed ID: 37239928

Doi: 10.3390/ijms24108581

Products & Services: Gene Synthesis

SARS-CoV-2 omicron variants harbor spike protein mutations responsible for their attenuated fusogenic phenotype

Authors: Seung Bum Park, Mohsin Khan, Sai Chaitanya Chiliveri, Xin Hu, Parker Irvin, Madeleine Leek, Ailis Grieshaber, Zongyi Hu, Eun Sun Jang, Ad Bax, T Jake Liang

Journal: Commun Biol

PubMed ID: 37225764

Doi: 10.1038/s42003-023-04923-x

Products & Services: Gene Synthesis

Refining the genomic determinants underlying escape from X-chromosome inactivation

Authors: Samantha Peeters, Tiffany Leung, Oriol Fornes, Rachelle A Farkas, Wyeth W Wasserman, Carolyn J Brown

Journal: NAR genomic and bioimformatics

PubMed ID: 37260510

Doi: 10.1093/nargab/lqad052

Products & Services: Gene Synthesis

Adaptive evolution to the natural and anthropogenic environment in a global invasive crop pest, the cotton bollworm

Authors: Minghui Jin, Henry L. North, Yan Peng, Hangwei Liu,, Bo Liu,, Ruiqing Pan, Yan Zhou, Weigang Zheng, Kaiyu Liu, Bo Yang, Lei Zhang, Qi Xu, Samia Elfekih,Wendy A. Valencia-Montoya, Tom Walsh, Peng Cui, Yongfeng Zhou, Kenneth Wilson, Chris Jiggins,Kongming Wu,and Yutao Xiao,

Journal: The Innovation

Doi: 10.1016/j.xinn.2023.100454

Products & Services: Gene Synthesis