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页码: 39/243 每页显示数量

Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses

Authors: Gwo-Yu Chuang, Chen-Hsiang Shen, Crystal Sao-Fong Cheung, Jason Gorman, Adrian Creanga, M Gordon Joyce, Kwanyee Leung, Reda Rawi, Lingshu Wang, Eun Sung Yang, Yongping Yang, Baoshan Zhang, Yi Zhang, Masaru Kanekiyo, Tongqing Zhou, Brandon J DeKosky, Barney S Graham, John R Mascola, Peter D Kwong

Journal: Front Immunol

PubMed ID: 34135892

Doi: 10.3389/fimmu.2021.662909

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Porcine circovirus type 2 infection attenuates the K63-linked ubiquitination of STING to inhibit IFN-β induction via p38-MAPK pathway

Authors: Xingchen Wu, Zhenyu Wang, Dan Qiao, Yu Yuan, Cong Han, Nan Yang, Ruizhen Li, Qian Du, Dewen Tong, Yong Huang

Journal: Vet Microbiol

PubMed ID: 33984793

Doi: 10.1016/j.vetmic.2021.109098

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A Dynamic, Ring-Forming Bactofilin Critical for Maintaining Cell Size in the Obligate Intracellular Bacterium

Authors: Mary R Brockett, Junghoon Lee, John V Cox, George W Liechti, Scot P Ouellette

Journal: Infect Immun

PubMed ID: 33941579

Doi: 10.1128/IAI.00203-21

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Direct small molecule ADaM-site AMPK activators reveal an AMPKγ3-independent mechanism for blood glucose lowering

Authors: Nicolas O Jørgensen, Rasmus Kjøbsted, Magnus R Larsen, Jesper B Birk, Nicoline R Andersen, Bina Albuquerque, Peter Schjerling, Russell Miller, David Carling, Christian K Pehmøller, Jørgen F P Wojtaszewski

Journal: Mol Metab

PubMed ID: 34033941

Doi: 10.1016/j.molmet.2021.101259

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The aminosterol Claramine inhibits β-secretase 1-mediated insulin receptor cleavage

Authors: Bénédicte Gaborit, Roland Govers, Alexandre Altié, Jean Michel Brunel, Pierre Morange, Franck Peiretti

Journal: J Biol Chem

PubMed ID: 34029592

Doi: 10.1016/j.jbc.2021.100818

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Selective and noncovalent targeting of RAS mutants for inhibition and degradation

Authors: Kai Wen Teng, Steven T Tsai, Takamitsu Hattori, Carmine Fedele, Akiko Koide, Chao Yang, Xuben Hou, Yingkai Zhang, Benjamin G Neel, John P O'Bryan, Shohei Koide

Journal: Nat Commun

PubMed ID: 33976200

Doi: 10.1038/s41467-021-22969-5

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In vitro profiling of orphan G protein coupled receptor (GPCR) constitutive activity

Authors: Lyndsay R Watkins, Cesare Orlandi

Journal: Br J Pharmacol

PubMed ID: 33784795

Doi: 10.1111/bph.15468

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Rituximab and Canakinumab Use During Lactation: No Detectable Serum Levels in Breastfed Infants

Authors: Nicole Bosshard, Astrid Zbinden, Klara Kristin Eriksson, Frauke Förger

Journal: Rheumatol Ther

PubMed ID: 33999372

Doi: 10.1007/s40744-021-00313-z

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Neither gonadotropin nor cumulus cell expansion is needed for the maturation of competent porcine oocytes in vitro

Authors: Bethany K Redel, Lee D Spate, Ye Yuan, Clifton N Murphy, R Michael Roberts, Randall S Prather

Journal: Biol Reprod

PubMed ID: 33962465

Doi: 10.1093/biolre/ioab090

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Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions

Authors: Andrea R Shiakolas, Kevin J Kramer, Daniel Wrapp, Simone I Richardson, Alexandra Schäfer, Steven Wall, Nianshuang Wang, Katarzyna Janowska, Kelsey A Pilewski, Rohit Venkat, Robert Parks, Nelia P Manamela, Nagarajan Raju, Emilee Friedman Fechter, Clinton M Holt, Naveenchandra Suryadevara, Rita E Chen, David R Martinez, Rachel S Nargi, Rachel E Sutton, Julie E Ledgerwood, Barney S Graham, Michael S Diamond, Barton F Haynes, Priyamvada Acharya, Robert H Carnahan, James E Crowe, Ralph S Baric, Lynn Morris, Jason S McLellan, Ivelin S Georgiev

Journal: Cell Rep Med

PubMed ID: 34056628

Doi: 10.1016/j.xcrm.2021.100313

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