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Ordered and disordered regions of the Origin Recognition Complex direct differential in vivo binding at distinct motif sequences

Authors: Michal Chappleboim, Segev Naveh-Tassa, Miri Carmi, Yaakov Levy, Naama Barkai

Journal: Nucleic Acids Res

PubMed ID: 38597680

Doi: 10.1093/nar/gkae249

Products & Services: Recombinant Proteins

A novel selenium analog of HDACi-based twin drug induces apoptosis and cell cycle arrest via CDC25A to improve prostate cancer therapy

Authors: Zhiyong Shi , Miaomiao Liu , Xiaowen Zhang , Jingyang Wang , Junwei Zhang , Zeyan Peng , Li Meng , Ruijing Wang ,Yang Xu , Jie Yan , Jianlin Cui , Shan Ren , Yang Gao , Yanming Wang , Zhi Qi

Journal: Theranostics

PubMed ID: 38948069

Doi: 10.7150/thno.92119

Products & Services: Nucleic Acid Purification & Analysis

An emerging antibacterial nanovaccine for enhanced chemotherapy by selectively eliminating tumor-colonizing bacteria

Authors: Linfu Chen a, Zheyu Kang a, Jingjing Shen a, Rui Zhao a, Yu Miao a, Lin Zhang b, Zixuan Zheng c, Zhemin Zhang c, Nanhui Liu a, Cheng Wang a, Huapan Fang a, Jun Zhou a, Yudong Wang b, Zhuang Liu a, Yang Yang c, Qian Chen

Journal: Science Bulletin

Doi: doi.org/10.1016/j.scib.2024.06.016

Products & Services: Molecular Biology Reagents

Highly biased agonism for GPCR ligands via nanobody tethering

Authors: Shivani Sachdev, Brendan A Creemer, Thomas J Gardella, Ross W Cheloha

Journal: Nat Commun

PubMed ID: 38824166

Doi: 10.1038/s41467-024-49068-5.

Products & Services: Proteins, Expression, Isolation and Analysis PCR Cloning and Subcloning

BRET-based biosensors for SARS-CoV-2 oligonucleotide detection

Authors: Asfia Sultana, Anupriya M Geethakumari, Zeyaul Islam, Prasanna R Kolatkar, Kabir H Biswas

Journal: Front Bioeng Biotechnol

PubMed ID: 38887615

Doi: 10.3389/fbioe.2024.1353479

Products & Services: Proteins, Expression, Isolation and Analysis

A growth selection system for sucrose synthases (SuSy): design and test

Authors: Gonzalo N Bidart, Se Hyeuk, Tobias Benedikt Alter, Lei Yang, Ditte Hededam Welner

Journal: AMB Express

PubMed ID: 38865019

Doi: 10.1186/s13568-024-01727-y

Products & Services: Molecular Biology Reagents

Repeat controlled human Plasmodium falciparum infections delay bloodstream patency and reduce symptoms

Authors: Patricia Ferrer, Andrea A Berry, Allison N Bucsan, Surendra K Prajapati, Karthik Krishnan, Michelle C Barbeau, David M Rickert, Sandra Mendoza Guerrero, Miho Usui, Yonas Abebe, Asha Patil, Sumana Chakravarty, Peter F Billingsley, Faith Pa'ahana-Brown, Kathy Strauss, Biraj Shrestha, Effie Nomicos, Gregory A Deye, B Kim Lee Sim, Stephen L Hoffman, Kim C Williamson, Kirsten E Lyke

Journal: Nat Commun

PubMed ID: 38890271

Doi: 10.1038/s41467-024-49041-2

Products & Services: Catalog Peptides

Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis

Authors: Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J Vavricka, Akira Hosoyama, Hiroko Kawasaki, Tomokazu Shirai, Michihiro Araki, Akira Nakagawa, Hiromichi Minami, Akihiko Kondo, Tomohisa Hasunuma

Journal: Microb Cell Fact

PubMed ID: 38879464

Doi: 10.1186/s12934-024-02453-7

Products & Services: Gene Synthesis

Designing monomeric IFNγ: the significance of domain-swapped dimer structure in IFNγ immune responses

Authors: Yota Goto, Takamitsu Miyafusa, Shinya Honda

Journal: J Biol Chem

PubMed ID: 38879015

Doi: 10.1016/j.jbc.2024.107464

Products & Services: Molecular Biology Reagents

Divergent humoral responses between males and females against 24 kDa excretory-secretory protein of Haemonchus contortus and influence of ovine β-globin polymorphism

Authors: Cintia Hiromi Okino, Simone Cristina Méo Niciura, Alessandro Pelegrine Minho, Sérgio Novita Esteves, Gláucia Roberta Melito, Hélio José Montassier, Ana Carolina de Souza Chagas

Journal: Dev Comp Immunol

PubMed ID: 38901502

Doi: 10.1016/j.dci.2024.105216

Products & Services: Recombinant Proteins