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页码: 282/5115 每页显示数量

TP5: A Novel Therapeutic Approach Targeting Aberrant and Hyperactive CDK5/p25 for the Treatment of Colorectal Carcinoma

Authors: Niranjana Amin, Herui Wang, Qi Song, Manju Bhaskar, Sharda Prasad Yadav, Mark R Gilbert, Harish Pant, Emeline Tabouret, Zhengping Zhuang

Journal: Int J Mol Sci

PubMed ID: 37511490

Doi: 10.3390/ijms241411733

Products & Services: Peptide Synthesis

Enhancement of the viability of T cells electroporated with DNA via osmotic dampening of the DNA-sensing cGAS–STING pathway

Authors: Jing An , Chuan-Ping Zhang , Hou-Yuan Qiu , Hong-Xia Zhang , Qiu-Bing Chen , Yu-Ming Zhang , Xin-Lin Lei , Cai-Xiang Zhang , Hao Yin , Ying Zhang

Journal: Nat Biomed Eng .

PubMed ID: 37500747

Doi: 10.1038/s41551-023-01073-7

Products & Services: CRISPR Plasmids

The combination of osimertinib with Raf inhibitor overcomes osimertinib resistance induced by KRAS amplification in EGFR-mutated lung cancer cells

Authors: Tae-Gul Lee, Hye-Min Kang, Seo Yun Kim, Hye-Ryoun Kim, Cheol Hyeon Kim

Journal: Exp Cell Res

PubMed ID: 37442265

Doi: 10.1016/j.yexcr.2023.113722

Products & Services: Proteins, Expression, Isolation and Analysis

Combined Inhibition of the TGF-β1/Smad Pathway by and to Reduce Inflammation and Fibrosis in Primary Sclerosing Cholangitis

Authors: Yu Shen, Baorong Jiang, Chenchen Zhang, Qian Wu, Lei Li, Ping Jiang

Journal: Int J Mol Sci

PubMed ID: 37446187

Doi: 10.3390/ijms241311010

Products & Services: Proteins, Expression, Isolation and Analysis

Viral manipulation of cell polarity signalling

Authors: Airah Javorsky, Patrick O Humbert, Marc Kvansakul

Journal: Biochim Biophys Acta Mol Cell Res

PubMed ID: 37437846

Doi: 10.1016/j.bbamcr.2023.119536

Products & Services: Molecular Biology Reagents

Macrophage infectivity potentiator protein, a peptidyl prolyl cis-trans isomerase, essential for Coxiella burnetii growth and pathogenesis

Authors: Aleksandra W Debowski, Nicole M Bzdyl, David R Thomas, Nichollas E Scott, Christopher H Jenkins, Jua Iwasaki, Emily A Kibble, Chen Ai Khoo, Nicolas J Scheuplein, Pamela M Seibel, Theresa Lohr, Georgie Metters, Charles S Bond, Isobel H Norville, Keith A Stubbs, Nicholas J Harmer, Ulrike Holzgrabe, Hayley J Newton, Mitali Sarkar-Tyson

Journal: PLoS Pathog

PubMed ID: 37399210

Doi: 10.1371/journal.ppat.1011491

Products & Services: Proteins, Expression, Isolation and Analysis

Investigating the aggregation perspective of Dengue virus proteome

Authors: Shivani Krishna Kapuganti, Kumar Udit Saumya, Deepanshu Verma, Rajanish Giri

Journal: Virology

PubMed ID: 37473502

Doi: 10.1016/j.virol.2023.07.010

Products & Services: Peptide Synthesis

Notch Intracellular Domains form Transcriptionally Active Heterodimeric Complexes on Sequence-paired Sites

Authors: Tana R Gazdik, Jacob J Crow, Tyler Lawton, Chloe J Munroe, Hannah Theriault, Travis M Wood, Allan R Albig

Journal: Res Sq

PubMed ID: 37546896

Doi: 10.21203/rs.3.rs-3147210/v1

Products & Services: Proteins, Expression, Isolation and Analysis

Pathogenic CANVAS (AAGGG) repeats stall DNA replication due to the formation of alternative DNA structures

Authors: Julia A Hisey, Elina A Radchenko, Silvia Ceschi, Anastasia Rastokina, Nicholas H Mandel, Ryan J McGinty, Gabriel Matos-Rodrigues, Alfredo Hernandez, André Nussenzweig, Sergei M Mirkin

Journal: biorxiv

PubMed ID: 37546920

Doi: 10.1101/2023.07.25.550509

Products & Services: Custom Vector Construction

Prokaryotic Gabija complex senses and executes nucleotide depletion and DNA cleavage for antiviral defense

Authors: Rui Cheng , Fengtao Huang , Xueling Lu , Yan Yan , Bingbing Yu , Xionglue Wang , Bin Zhu

Journal: Cell Host Microbe .

PubMed ID: 37480847

Doi: 10.1016/j.chom.2023.06.014

Products & Services: Custom DNA/RNA Oligos