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A thermostable type I-B CRISPR-Cas system for orthogonal and multiplexed genetic engineering

Authors: Zhiheng Yang , Zilong Li , Bixiao Li , Ruihong Bu , Gao-Yi Tan , Zhengduo Wang , Hao Yan , Zhenguo Xin , Guojian Zhang , Ming Li , Hua Xiang, Lixin Zhang , Weishan Wang

Journal: Nat Commun .

PubMed ID: 37794017

Doi: 10.1038/s41467-023-41973-5

Products & Services: Custom DNA/RNA Oligos CRISPR Libraries

Histone Abundance Quantification via Flow Cytometry of Htb2-GFP Allows Easy Monitoring of Cell Cycle Perturbations in Living Yeast Cells, Comparable to Standard DNA Staining

Authors: Maria V Kulakova, Eslam S M O Ghazy, Fedor Ryabov, Yaroslav M Stanishevskiy, Michael O Agaphonov, Alexander I Alexandrov

Journal: J Fungi (Basel)

PubMed ID: 37888289

Doi: 10.3390/jof9101033

Products & Services: Proteins, Expression, Isolation and Analysis

Glycan heterogeneity as a cause of the persistent fraction in HIV-1 neutralization

Authors: Rajesh P Ringe, Philippe Colin, Gabriel Ozorowski, Joel D Allen, Anila Yasmeen, Gemma E Seabright, Jeong Hyun Lee, Aleksandar Antanasijevic, Kimmo Rantalainen, Thomas Ketas, John P Moore, Andrew B Ward, Max Crispin, P J Klasse

Journal: PLoS Pathog

PubMed ID: 37903160

Doi: 10.1371/journal.ppat.1011601

Products & Services: Proteins, Expression, Isolation and Analysis

VP2 residue N142 of coxsackievirus A10 is critical for the interaction with KREMEN1 receptor and neutralizing antibodies and the pathogenicity in mice

Authors: Xue Li, Zeyu Liu, Xingyu Yan, Yuan Tian, Kexin Liu, Yue Zhao, Jiang Shao, Pei Hao, Chao Zhang

Journal: PLoS Pathog

PubMed ID: 37788227

Doi: 10.1371/journal.ppat.1011662

Products & Services: Proteins, Expression, Isolation and Analysis

One ring closer to a closure: the crystal structure of the ES hydroxymethylbilane synthase intermediate

Authors: Helene J Bustad, Marthe S Christie, Mikko Laitaoja, Aasne K Aarsand, Aurora Martinez, Janne Jänis, Juha P Kallio

Journal: FEBS J

PubMed ID: 37863644

Doi: 10.1111/febs.16982

Products & Services: Proteins, Expression, Isolation and Analysis

Improved prime editing allows for routine predictable gene editing in Physcomitrium patens

Authors: Pierre-François Perroud, Anouchka Guyon-Debast, Josep M Casacuberta, Wyatt Paul, Jean-Philippe Pichon, David Comeau, Fabien Nogué

Journal: J Exp Bot

PubMed ID: 37243510

Doi: 10.1093/jxb/erad189

Products & Services: Molecular Biology Reagents

The Functional Characteristics and Soluble Expression of Saffron CCD2

Authors: Ying Wang, Siqi Li, Ze Zhou, Lifen Sun, Jing Sun, Chuanpu Shen, Ranran Gao, Jingyuan Song, Xiangdong Pu

Journal: Int J Mol Sci

PubMed ID: 37894770

Doi: 10.3390/ijms242015090

Products & Services: Gene Synthesis

Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells

Authors: Mihir B Doshi, Namgyu Lee, Tenzin Tseyang, Olga Ponomarova, Hira Lal Goel, Meghan Spears, Rui Li, Lihua Julie Zhu, Christopher Ashwood, Karl Simin, Cholsoon Jang, Arthur M Mercurio, Albertha J M Walhout, Jessica B Spinelli, Dohoon Kim

Journal: Nature

PubMed ID: 37880368

Doi: 10.1038/s41586-023-06676-3

Products & Services: Custom Vector Construction

A genetic screen identifies BEND3 as a regulator of bivalent gene expression and global DNA methylation

Authors: Lounis Yakhou, Anaelle Azogui, Nikhil Gupta, Julien Richard Albert, Fumihito Miura, Laure Ferry, Kosuke Yamaguchi, Sarah Battault, Pierre Therizols, Frédéric Bonhomme, Elouan Bethuel, Arpita Sarkar, Maxim V C Greenberg, Paola B Arimondo, Gael Cristofari, Olivier Kirsh, Takashi Ito, Pierre-Antoine Defossez

Journal: Nucleic Acids Res

PubMed ID: 37650637

Doi: 10.1093/nar/gkad719

Products & Services: Custom DNA/RNA Oligos

A novel nanobody-based HER2-targeting antibody exhibits potent synergistic antitumor efficacy in trastuzumab-resistant cancer cells

Authors: Xinlin Liu, Linli Luan, Xi Liu, Dingwen Jiang, Junwen Deng, Jiazhen Xu, Yang Yuan, Jiyao Xing, Bingguan Chen, Dongming Xing, Haiming Huang

Journal: Front Immunol

PubMed ID: 37954614

Doi: 10.3389/fimmu.2023.1292839

Products & Services: Monoclonal Antibody Services