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Optimizing interleukin-6 and 8 expression, clarification and purification in plant cell packs and plants for application in advanced therapy medicinal products and cellular agriculture

Authors: P Opdensteinen, J F Buyel

Journal: J Biotechnol

PubMed ID: 38740307

Doi: 10.1016/j.jbiotec.2024.05.003

Products & Services: Catalog Antibody

HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice

Authors: Laiqiang Chen, Yiyang Qin, Tingting Guo, Wenzhen Zhu, Jingpan Lin, Tingting Xing, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Xiang Li, Peng Yin, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: Cell Death Dis

PubMed ID: 38744826

Doi: 10.1038/s41419-024-06716-4

Products & Services: Proteins, Expression, Isolation and Analysis

Evolved histone tail regulates 53BP1 recruitment at damaged chromatin

Authors: Jessica L Kelliher, Melissa L Folkerts, Kaiyuan V Shen, Wan Song, Kyle Tengler, Clara M Stiefel, Seong-Ok Lee, Eloise Dray, Weixing Zhao, Brian Koss, Nicholas R Pannunzio, Justin W Leung

Journal: Nat Commun

PubMed ID: 38821984

Doi: 10.1038/s41467-024-49071-w

Products & Services: Catalog Peptides

A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction

Authors: Baiyang Sun, Zihe Liang, Yupeng Wang, Yue Yu, Xiaobing Zhou, Xingchao Geng, Bo Li

Journal: Toxicology

PubMed ID: 38740170

Doi: 10.1016/j.tox.2024.153829

Products & Services: Proteins, Expression, Isolation and Analysis

Development of a Fully Protective Pandemic Avian Influenza Subunit Vaccine in Insect Pupae

Authors: Ana Falcón, Susana Martínez-Pulgarín, Sergi López-Serrano, Edel Reytor, Miguel Cid, Maria Del Carmen Nuñez, Lorena Córdoba, Ayub Darji, José M Escribano

Journal: Viruses

PubMed ID: 38932122

Doi: 10.3390/v16060829

Products & Services: Gene Synthesis

Structural mechanisms of Tad pilus assembly and its interaction with an RNA virus

Authors: Yuhang Wang, Matthew Theodore, Zhongliang Xing, Utkarsh Narsaria, Zihao Yu, Lanying Zeng, Junjie Zhang

Journal: SCIENCE ADVANCES

PubMed ID: 38701202

Doi: 10.1126/sciadv.adl4450

Products & Services: PCR Cloning and Subcloning

TRIM37 is a primate-specific E3 ligase for Huntingtin and accounts for the striatal degeneration in Huntington’s disease

Authors: Yiyang Qin, Laiqiang Chen, Wenzhen Zhu, Jiahong Song, Jingpan Lin, Yuwei Li, Jiawei Zhang, Xichen Song, Tingting Xing, Tingting Guo, Xuezhi Duan, Yiran Zhang, Eshu Ruan, Qi Wang, Bang Li, Weili Yang , Peng Yin, Xiao-Xin Yan, Shihua Li, Xiao-Jiang Li, Su Yang

Journal: SCIENCE ADVANCES

PubMed ID: 38758800

Doi: 10.1126/sciadv.adl2036

Products & Services: Proteins, Expression, Isolation and Analysis

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

Authors: Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón & Andreas Hougaard Laustsen

Journal: Nat Commun

PubMed ID: 38773068

Doi: 10.1038/s41467-024-48539-z

Products & Services: Gene Synthesis

Impact of N-Glycosylation on Protein Structure and Dynamics Linked to Enzymatic C–H Activation in the M. oryzae Lipoxygenase

Authors: Chris Whittington, Ajay Sharma, S Gage Hill, Anthony T Iavarone, Brian M Hoffman, Adam R Offenbacher

Journal: Biochemistry

PubMed ID: 38690768

Doi: 10.1021/acs.biochem.4c00109

Products & Services: Mutagenesis Services

Manganese-dependent transcription regulation by MntR and PerR in Thermus thermophilus HB8

Authors: John K Barrows, Kamya A Stubbs, Irina F Padilla-Montoya, Thomas C Leeper, Michael W Van Dyke