A short D-enantiomeric antimicrobial peptide with potent immunomodulatory and antibiofilm activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii.
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| Peptide Synthesis |
Peptides were synthesized using solid-phase 9-fluorenylmethoxy carbonyl (Fmoc) chemistry (GenScript, Piscataway, NJ).To determine the peptides’ ability to bind to LPS, a Limulus amoebocyte lysate (LAL) kit (Genscript, USA Inc.) was utilized, as described in previous reports52. |
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