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Costunolide induces mitochondria-mediated apoptosis in human gastric adenocarcinoma BGC-823 cells.

BMC Complement Altern Med. 2019-06; 
YanZhanpeng,XuTingting,AnZhentao,HuYing,ChenWanzhen,MaJinxia,ShaoChangle,ZhuFan
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Gene Synthesis GAPDH gene is the reference gene. Q-PCR primers were synthesized by GenScript Biotech (Nanjing, China) and are listed in Table 1. Get A Quote

摘要

Costunolide, a sesquiterpene lactone extracted from Radix Aucklandiae, has the activity against multiple cancers. However, the effect of costunolide on gastric cancer (GC) have remained to be ambiguous. In this study, we investigated the underlying mechanisms of apoptosis induced by costunolide in human gastric adenocarcinoma BGC-823 cells in vitro and in vivo.

关键词

Apoptosis,Costunolide,Gastric cancer,Xenografted nude
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