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Timing of exposure to environmental adjuvants is critical to mitigate peanut allergy

J Allergy Clin Immunol. 2020; 
Johanna M Smeekens, Robert M Immormino, Michael D Kulis, Timothy P Moran
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Endotoxin Detection & Removal System … Endotoxin was measured by ToxinSensor Endotoxin Detection System (GenScript, Piscataway, NJ); bacterial DNA by qPCR using primers specific for bacterial ribosomal DNA3; β-1,3-glucans by Glucatell® Kit (Associates of Cape … Get A Quote

摘要

Toll-like receptor ligands in indoor dust act as environmental adjuvants to promote sensitization to inhaled peanut in mice. The timing of exposure to environmental adjuvants relative to peanut is a determinant of peanut allergy development.

关键词

Airway sensitization, Anaphylaxis, Food allergy, Indoor dust, Peanut allergy, Toll-like receptors
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