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Charting elimination in the pandemic: a SARS-CoV-2 serosurvey of blood donors in New Zealand

Epidemiol Infect. 2021-07; 
Lauren H Carlton, Tiffany Chen, Alana L Whitcombe, Reuben McGregor, Greg Scheurich, Campbell R Sheen, James M Dickson, Chris Bullen, Annie Chiang, Daniel J Exeter, Janine Paynter, Michael G Baker, Richard Charlewood, Nicole J Moreland
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Recombinant Proteins … Viral Neutralization Test (sVNT) (GenScript, New Jersey, USA) and the values deemed seropositive if above the cut-off on both commercial assays. Sensitivity … Get A Quote

摘要

New Zealand has a strategy of eliminating SARS-CoV-2 that has resulted in a low incidence of reported coronavirus-19 disease (COVID-19). The aim of this study was to describe the spread of SARS-CoV-2 in New Zealand via a nationwide serosurvey of blood donors. Samples (n = 9806) were collected over a month-long period (3 December 2020-6 January 2021) from donors aged 16-88 years. The sample population was geographically spread, covering 16 of 20 district health board regions. A series of Spike-based immunoassays were utilised, and the serological testing algorithm was optimised for specificity given New Zealand is a low prevalence setting. Eighteen samples were seropositive for SARS-CoV-2 antibodies, six of whic... More

关键词

COVID-19, New Zealand, SARS-CoV-2, Spike, elimination, receptor binding domain, seroprevalence, serosurvey
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