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目录产品 » Human Lambda Light Chain (2D54), mAb, Mouse

Human Lambda Light Chain (2D54), mAb, Mouse

Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response. Ig is composed of two identical light chains and two identical heavy chains. FLC contains two types: kappa free light chain (KFLC) and lambda free light chain (LFLC). The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies. It is useful for the identification of certain non-Hodgkin’s lymphomas, leukemias and plasmacytomas. Immunohistochemistry is commonly applied for the detection of free light chains.
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Description

Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response. Ig is composed of two identical light chains and two identical heavy chains. FLC contains two types: kappa free light chain (KFLC) and lambda free light chain (LFLC). The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies. It is useful for the identification of certain non-Hodgkin’s lymphomas, leukemias and plasmacytomas. Immunohistochemistry is commonly applied for the detection of free light chains.
Synonyms

Human Lambda Light Chain (2D54), mAb, Mouse

Note

GenScript can customize this product per customer's request including product size, buffer components,etc.

产品概述
Specificity Specific to Human Lambda light chain, does not react with human Kappa light chain
Subclass IgG2a
Host Species Mouse
Conjugation Unconjugated
Antigen Species Human

产品属性
Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Formulation 1) PBS, pH 7.4, containing 0.03% Proclin 300
2) 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 *
*: For new batch since 09/01/2018, please refer to COA.
Concentration ≥2mg/ml
Clone ID 2D54
Storage For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

应用指导
ELISA/IHC/Flow cytometry assay

技术背景
Target Background Immunoglobulins (Ig) and free light chains (FLC) is involved in humoral immune response. Ig is composed of two identical light chains and two identical heavy chains. FLC contains two types: kappa free light chain (KFLC) and lambda free light chain (LFLC). The expression of Kappa or Lambda is greatly increased in multiple myeloma or other B cell malignancies. It is useful for the identification of certain non-Hodgkin’s lymphomas, leukemias and plasmacytomas. Immunohistochemistry is commonly applied for the detection of free light chains.

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