Dose dependent stimulation of intracellular cAMP mobilization upon treatment with NECA. The EC50 of NECA on CHO-K1/mouse ADORA2A cells was 9.57 nM.
Dose dependent stimulation of intracellular cAMP mobilization upon treatment with NECA. The EC50 of NECA on CHO-K1/mouse ADORA2A cells was 9.57 nM.
Dose dependent stimulation of intracellular cAMP mobilization upon treatment with NECA. The EC50 of NECA on CHO-K1/mouse ADORA2A cells was 9.57 nM.
CHO-K1/mouse ADORA2A Stable Cell Line
The adenosine receptors ADORA2A are Gs-coupled GPCRs expressed in the thymus gland, heart, lung, kidney, brain, platelets, spleen and leukocytes. ADORA2A down-regulates chemokine receptor function and inhibits platelet aggregation. ADORA2A antagonists may be useful as therapy for Parkinson's disease.
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