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SafeEdit RAB11A sgRNA

SafeEdit RAB11A sgRNA (HPLC)
KIOK2
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Description HPLC purified SafeEdit sgRNA with modifications targeting the first exon of house-keeping gene RAB11A, member RAS oncogene family [Homo sapiens (human)]

For customized sgRNA synthesis service, please visit: https://www.genscript.com/crispr-cas9-single-guide-RNA-and-ribonucleoprotein.html

[Reference] Roth. et al. Reprogramming human T cell function and specificity with non-viral genome targeting. Nature 2018, 559(7714): 405-409.
Sequence
mG*mG*mU*AGUCGUACUCGUCGUCGGUUUUAGAGCUAGAAAUAGCAAGUUAAAA
UAAGGCUAGUCCGUUAUCAACUUGAAAAAGUGGCACCGAGUCGGUGCU*mU*mU*mU
m=2'O-Methyl RNA; *=Phosphorothioate
Storage Condition Stable for at least 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Quality Specifications
Item Specifications
Molecular Weight ≤+/- 0.05% from theoretical molecular weight by mass spectrometry
Purity ≥90% by RNase-free HPLC

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