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目录产品 » CD30, hFc, Human
CD30, HFc, Human

Recombinant CD30, hFc, Human on SDS-PAGE under reducing conditions, the purity is greater than 95%.

CD30, hFc, Human

CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
Z03641
￥1600

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产品简介
Species Human
Protein Construction
CD30 (Phe19-Lys379)
Accession # P28908		 hFc
N-term C-term
Purity > 95% as analyzed by SDS-PAGE
Endotoxin Level ≤ 1 EU/μg of protein by LAL method
Expression System Human Cells
Apparent Molecular Weight 90~120 kDa, on SDS-PAGE under reducing conditions.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Reconstitution It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in distilled water up to 100 μg/ml.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4-7°C and up to 3 months at -20 °C or below. Avoid repeated freeze-thaw cycles.

图例
  • CD30, HFc, Human
    • CD30, HFc, Human

    Recombinant CD30, hFc, Human on SDS-PAGE under reducing conditions, the purity is greater than 95%.


技术背景
Target Background CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family, which regulates proliferation/apoptosis and antibody responses. CD30 is expressed by activated, but not by resting, T and B cells. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis. CD30 has been considered as a specific diagnostic biomarker of anaplastic large cell lymphoma (ALCL) and classical Hodgkin lymphoma (cHL). CD30 is also a biomarker used for targeted therapy by an antibody–drug conjugate.
Synonyms CD30L receptor; Ki-1 antigen; CD_antigen: CD30; TNFRSF8; D1S166E; Lymphocyte activation antigen CD30; Tumor necrosis factor receptor superfamily member 8

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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