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Cys Site-Directed Mutagenesis of the Human SLC1A5 (ASCT2) Transporter: Structure/Function Relationships and Crucial Role of Cys467 for Redox Sensing and Glutamine Transport.
Authors: Scalise Mariafrancesca，Pochini Lorena，Console Lara，Pappacoda Gilda，Pingitore Piero，Hedfalk Kristina，Indiveri Ce
Journal: Int J Mol Sci
PubMed ID: 29495336
Doi: 10.3390/ijms19030648
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Pro region engineering of nerve growth factor by deep mutational scanning enables a yeast platform for conformational epitope mapping of anti-NGF monoclonal antibodies.
Authors: Medina-Cucurella AV, Zhu Y, Bowen SJ, Bergeron LM, Whitehead TA,,.
Journal: Biotechnol Bioeng
PubMed ID: 29663315
Doi: 10.1002/bit.26706
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Role of Extracellular Vesicle Surface Proteins in the Pharmacokinetics of Extracellular Vesicles.
Authors: Charoenviriyakul C, Takahashi Y, Morishita M, Nishikawa M, Takakura Y.
Journal: Mol Pharm
PubMed ID: 29382201
Doi: 10.1021/acs.molpharmaceut.7b00950
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The mitochondrial single-stranded DNA binding protein from S cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers
Authors: Singh SP, Kukshal V, De Bona P, Antony E, Galletto R.
Journal: Nucleic Acids Res
PubMed ID: 29931186
Doi: 10.1093/nar/gky530
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Vaccination of sows with a dendritic cell-targeted porcine epidemic diarrhea virus S1 protein-based candidate vaccine reduced viral shedding but exacerbated gross pathological lesions in suckling neonatal piglets.
Authors: Subramaniam S, Yugo DM, Heffron CL, Rogers AJ, Sooryanarain H, LeRoith T, Overend C,, Cao D, Meng XJ.
Journal: J Gen Virol
PubMed ID: 29300158
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Identification of MazF Homologue in Legionella pneumophila Which Cleaves RNA at the AACU Sequence.
Authors: Shaku M, Park JH, Inouye M, Yamaguchi Y,.
Journal: J Mol Microbiol Biotechnol
PubMed ID: 30893701
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A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling.
Authors: Soto-VelasquezMonica，HayesMichael P，AlpsoyAktan，DykhuizenEmily C，WattsV
Journal: Mol. Pharmacol.
PubMed ID: 29950405
Doi: 10.1124/mol.118.111849
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CD95/Fas ligand mRNA is toxic to cells.
Authors: PutzbachWill，Haluck-KangasAshley，GaoQuan Q，SarshadAishe A，BartomElizabeth T，StultsAustin，QadirAbdul S，HafnerMarkus，PeterMarc
Journal: Elife
PubMed ID: 30324908
Doi: 10.7554/eLife.38621
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The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis.
Authors: PackianathanCharles，KandaveluPalani，RosenBar
Journal: Biochemistry
PubMed ID: 29894638
Doi: 10.1021/acs.biochem.8b00457
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TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3Kγ for Suppression of Inflammatory Responses.
Authors: Luo L, Wall AA, Tong SJ, Hung Y, Xiao Z, Tarique AA, Sly PD, Fantino E, Marzolo MP, Stow JL.
Journal: Cell Rep
PubMed ID: 30208326
Doi: 10.1016/j.celrep.2018.08.028
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