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Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5

Authors: Lisa Merklinger, Johannes Bauer, Per A Pedersen, Rune Busk Damgaard, J Preben Morth

Journal: Life Sci Alliance

PubMed ID: 35459736

Doi: 10.26508/lsa.202101309

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Non-homologous End Joining-Mediated Insertional Mutagenesis Reveals a Novel Target for Enhancing Fatty Alcohols Production in

Authors: Mengxu Li, Jinlai Zhang, Qiuyan Bai, Lixia Fang, Hao Song, Yingxiu Cao

Journal: Front Microbiol

PubMed ID: 35547152

Doi: 10.3389/fmicb.2022.898884

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Metal binding and interdomain thermodynamics of mammalian metallothionein-3: enthalpically favoured Cu supplants entropically favoured Zn to form Cu clusters under physiological conditions

Authors: Matthew R Mehlenbacher, Rahma Elsiesy, Rabina Lakha, Rhiza Lyne E Villones, Marina Orman, Christina L Vizcarra, Gabriele Meloni, Dean E Wilcox, Rachel N Austin

Journal: Chem Sci

PubMed ID: 35655557

Doi: 10.1039/d2sc00676f

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TFPIisacoloniccryptreceptorforTcdBfromhypervirulentclade2C.difficile

Authors: Jianhua Luo , Qi Yang , Xiaofeng Zhang , Yuanyuan Zhang , Li Wan , Xiechao Zhan , Yao Zhou , Liuqing He , Danyang Li , Dazhi Jin , Ying Zhen , Jing Huang , Yanyan Li , Liang Tao

Journal: Cell

PubMed ID: 35303428

Doi: 10.1016/j.cell.2022.02.010

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A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination

Authors: Karen Colwill, Yannick Galipeau, Matthew Stuible, Christian Gervais, Corey Arnold, Bhavisha Rathod, Kento T Abe, Jenny H Wang, Adrian Pasculescu, Mariam Maltseva, Lynda Rocheleau, Martin Pelchat, Mahya Fazel-Zarandi, Mariam Iskilova, Miriam Barrios-Rodiles, Linda Bennett, Kevin Yau, François Cholette, Christine Mesa, Angel X Li, Aimee Paterson, Michelle A Hladunewich, Pamela J Goodwin, Jeffrey L Wrana, Steven J Drews, Samira Mubareka, Allison J McGeer, John Kim, Marc-André Langlois, Anne-Claude Gingras, Yves Durocher

Journal: Clin Transl Immunology

PubMed ID: 35356067

Doi: 10.1002/cti2.1380

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A peroxisomal heterodimeric enzyme is involved in benzaldehyde synthesis in plants

Authors: Xing-Qi Huang, Renqiuguo Li, Jianxin Fu, Natalia Dudareva

Journal: Nat Commun

PubMed ID: 35292635

Doi: 10.1038/s41467-022-28978-2

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Human antibody recognizing a quaternary epitope in the Puumala virus glycoprotein provides broad protection against orthohantaviruses

Authors: Eva Mittler, Anna Z Wec, Janne Tynell, Pablo Guardado-Calvo, Julia Wigren-Byström, Laura C Polanco, Cecilia M O'Brien, Megan M Slough, Dafna M Abelson, Alexandra Serris, Mrunal Sakharkar, Gerard Pehau-Arnaudet, Russell R Bakken, James C Geoghegan, Rohit K Jangra, Markus Keller, Larry Zeitlin, Olli Vapalahti, Rainer G Ulrich, Zachary A Bornholdt, Clas Ahlm, Felix A Rey, John M Dye, Steven B Bradfute, Tomas Strandin, Andrew S Herbert, Mattias N E Forsell, Laura M Walker, Kartik Chandran

Journal: Sci Transl Med

PubMed ID: 35294259

Doi: 10.1126/scitranslmed.abl5399

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Invalidation of dieckol and 1,2,3,4,6-pentagalloylglucose (PGG) as SARS-CoV-2 main protease inhibitors and the discovery of PGG as a papain-like protease inhibitor

Authors: Haozhou Tan, Chunlong Ma, Jun Wang

Journal: Res Sq

PubMed ID: 35378761

Doi: 10.21203/rs.3.rs-1490282/v1

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Glycosite-deleted mRNA of SARS-CoV-2 spike protein as a broad-spectrum vaccine

Authors: Chung-Yi Wu, Cheng-Wei Cheng, Chih-Chuan Kung, Kuo-Shiang Liao, Jia-Tsrong Jan, Che Ma, Chi-Huey Wong

Journal: Proc Natl Acad Sci U S A

PubMed ID: 35149556

Doi: 10.1073/pnas.2119995119

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Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

Authors: Veronica Gast, Anna Sandegren, Finn Dunås, Siri Ekblad, Rezan Güler, Staffan Thorén, Marta Tous Mohedano, Mikael Molin, Martin K M Engqvist, Verena Siewers

Journal: Microb Cell Fact

PubMed ID: 35264156

Doi: 10.1186/s12934-022-01761-0

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