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In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a single ESI-MS spectrum

Authors: Luis Ariel Espinosa, Yassel Ramos, Ivan Andújar, Enso Onill Torres, Gleysin Cabrera, Alejandro Martín, Diamilé Roche, Glay Chinea, Mónica Becquet, Isabel González, Camila Canaán-Haden, Elías Nelson, Gertrudis Rojas, Beatriz Pérez-Massón, Dayana Pérez-Martínez, Tamy Boggiano, Julio Palacio, Sum Lai Lozada Chang, Lourdes Hernández, Kathya Rashida de la Luz Hernández, Saloheimo Markku, Marika Vitikainen, Yury Valdés-Balbín, Darielys Santana-Medero, Daniel G Rivera, Vicente Vérez-Bencomo, Mark Emalfarb, Ronen Tchelet, Gerardo Guillén, Miladys Limonta, Eulogio Pimentel, Marta Ayala, Vladimir Besada, Luis Javier González

Journal: Anal Bioanal Chem

PubMed ID: 34739558

Doi: 10.1007/s00216-021-03721-w

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Immunogenic and efficacious SARS-CoV-2 vaccine based on resistin-trimerized spike antigen SmT1 and SLA archaeosome adjuvant

Authors: Bassel Akache, Tyler M Renner, Anh Tran, Lise Deschatelets, Renu Dudani, Blair A Harrison, Diana Duque, Julie Haukenfrers, Martin A Rossotti, Francis Gaudreault, Usha D Hemraz, Edmond Lam, Sophie Régnier, Wangxue Chen, Christian Gervais, Matthew Stuible, Lakshmi Krishnan, Yves Durocher, Michael J McCluskie

Journal: Sci Rep

PubMed ID: 34750472

Doi: 10.1038/s41598-021-01363-7

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Enzymatic Synthesis of 3'-5', 3'-5' Cyclic Dinucleotides, Their Binding Properties to the Stimulator of Interferon Genes Adaptor Protein, and Structure/Activity Correlations

Authors: Barbora Novotná, Lucie Holá, Monika Staś, Ondrej Gutten, Miroslav Smola, Martin Zavřel, Zdeněk Vavřina, Miloš Buděšínský, Radek Liboska, Florian Chevrier, Juraj Dobiaš, Evzen Boura, Lubomír Rulíšek, Gabriel Birkuš

Journal: Biochemistry

PubMed ID: 34788017

Doi: 10.1021/acs.biochem.1c00692

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Two C1-oxidizing AA9 lytic polysaccharide monooxygenases from Sordaria brevicollis differ in thermostability, activity, and synergy with cellulase

Authors: Xi Zhang, Kaixiang Chen, Liangkun Long, Shaojun Ding

Journal: Appl Microbiol Biotechnol

PubMed ID: 34748039

Doi: 10.1007/s00253-021-11677-1

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SEC23A rescues SEC23B-deficient congenital dyserythropoietic anemia type II

Authors: Richard King, Zesen Lin, Ginette Balbin-Cuesta, Gregg Myers, Ann Friedman, Guojing Zhu, Beth McGee, Thomas L Saunders, Ryo Kurita, Yukio Nakamura, James Douglas Engel, Pavan Reddy, Rami Khoriaty

Journal: Sci Adv

PubMed ID: 34818036

Doi: 10.1126/sciadv.abj5293

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Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus

Authors: Ebru Destan, Busra Yuksel, Bradley B Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A Francis, Hasan DeMirci

Journal: Sci Rep

PubMed ID: 34819551

Doi: 10.1038/s41598-021-02180-8

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Proteolytic processing of plant proteins by potyvirus NIa proteases

Authors: Huogen Xiao, Etienne Lord, Hélène Sanfaçon

Journal: J Virol

PubMed ID: 34757836

Doi: 10.1128/JVI.01444-21

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Structure of native HIV-1 cores and their interactions with IP6 and CypA

Authors: Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Böcking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang

Journal: Sci Adv

PubMed ID: 34797722

Doi: 10.1126/sciadv.abj5715

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Allelic variants of full-length VAR2CSA, the placental malaria vaccine candidate, differ in antigenicity and receptor binding affinity

Authors: Jonathan P Renn, Justin Y A Doritchamou, Bergeline C Nguemwo Tentokam, Robert D Morrison, Matthew V Cowles, Martin Burkhardt, Rui Ma, Niraj H Tolia, Michal Fried, Patrick E Duffy

Journal: Commun Biol

PubMed ID: 34799664

Doi: 10.1038/s42003-021-02787-7

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Backbone H, N, and C resonance assignments of the non-structural protein NS2B of Zika virus

Authors: Beatriz Rosa Penna, Danielle Maria P de Oliveira, Cristiane Dinis Anobom, Ana Paula Valente

Journal: Biomol NMR Assign

PubMed ID: 34817802

Doi: 10.1007/s12104-021-10055-2

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