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Acceptor substrate determines donor specificity of an aromatic prenyltransferase: expanding the biocatalytic potential of NphB

Authors: Bryce P Johnson, Erin M Scull, Dustin A Dimas, Tejaswi Bavineni, Chandrasekhar Bandari, Andrea L Batchev, Eric D Gardner, Susan L Nimmo, Shanteri Singh

Journal: Appl Microbiol Biotechnol

PubMed ID: 32189045

Doi: 10.1007/s00253-020-10529-8

Products & Services: Codon Optimization

Pathway-specific enzymes from bamboo and crop leaves biosynthesize anti-nociceptive C-glycosylated flavones

Authors: Sun Y, Chen Z, Yang J, Mutanda I, Li S, Zhang Q, Zhang Y, Zhang Y, Wang Y

Journal: Communications Biology

PubMed ID: 32144397

Doi: 10.1038/s42003-020-0834-3

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Structure-Guided Mutagenesis Alters Deubiquitinating Activity and Attenuates Pathogenesis of a Murine Coronavirus

Authors: Deng X, Chen Y, Mielech AM, Hackbart M, Kesely KR, Mettelman RC, O'Brien A, Chapman ME, Mesecar AD, Baker SC

Journal: J Virol

PubMed ID: 32188728

Doi: 10.1128/JVI.01734-19

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Characterization of novel monoclonal antibodies against MERS-coronavirus spike protein

Authors: JunghyunGoo,YujiJeong,Young-ShinPark,EunjiYang,Dae-ImJung,SemiRho,UniPark,HyeyeongSung,Pil-GuPark,Jung-ahChoi,Sang HwanSeo,Nam HyuckCho,HyejaLee,Jae MyunLee,Jae-OukKim,MankiSong

Journal: Virus Research

Doi: 10.1016/j.virusres.2020.197863

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Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights

Authors: Rieux C, Goffinont S, Coste F, Tber Z, Cros J, Roy V, Guérin M, Gaudon V, Bourg S, Biela A, Aucagne V, Agrofoglio L, Garnier N, Castaing B

Journal: Int J Mol Sci

PubMed ID: 32192183

Doi: 10.3390/ijms21062058

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Carboxy-Terminal Phosphoregulation of the Long Splice Isoform of Free-Fatty Acid Receptor-4 Mediates -Arrestin Recruitment and Signaling to ERK1/2

Authors: Ilya S Senatorov, Ameneh Cheshmehkani, Rebecca N Burns, Kirti Singh, Nader H Moniri

Journal: Mol Pharmacol