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Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation

Authors: Greig JA, Nguyen TA, Lee M, Holehouse AS, Posey AE, Pappu RV, Jedd G.

Journal: Mol Cell

PubMed ID: 32048997

Doi: 10.1016/j.molcel.2020.01.025

Products & Services: Gene Synthesis

Garcinoic Acid Is a Natural and Selective Agonist of Pregnane X Receptor

Authors: Bartolini D, De Franco F, Torquato P, Marinelli R, Cerra B, Ronchetti R, Schon A, Fallarino F, De Luca A, Bellezza G, Ferri I, Sidoni A, Walton WG, Pellock SJ, Redinbo MR, Mani S, Pellicciari R, Gioiello A, Galli F.

Journal: J Med Chem

PubMed ID: 32160459

Doi: 10.1021/acs.jmedchem.0c00012

Products & Services: Gene Synthesis

Genetic and genomic studies of pathogenic EXOSC2 mutations in the newly described disease SHRF implicate the autophagy pathway in disease pathogenesis

Authors: Yang X, , Bayat V, DiDonato N, Zhao Y, Zarnegar B, Siprashvili Z, Lopez-Pajares V, Sun T, Tao S, Li C, Rump A, Khavari P, Lu B, .

Journal: Hum Mol Genet

PubMed ID: 31628467

Doi: 10.1093/hmg/ddz251

Products & Services: Gene Synthesis

Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration

Authors: Cipriani V, , Lorés-Motta L, He F, Fathalla D, Tilakaratna V, McHarg S, Bayatti N, Acar İE, Hoyng CB, Fauser S, Moore AT, , Yates JRW, , de Jong EK, Morgan BP, den Hollander AI, Bishop PN, Clark SJ, .

Journal: Nat Commun

PubMed ID: 32034129

Doi: 10.1038/s41467-020-14499-3

Products & Services: Gene Synthesis

The Rare IL22RA2 Signal Peptide Coding Variant rs28385692 Decreases Secretion of IL-22BP Isoform-1, -2 and -3 and Is Associated with Risk for Multiple Sclerosis

Authors: Gómez-Fernández P, Lopez de Lapuente Portilla A, Astobiza I, Mena J, Urtasun A, Altmann V, Matesanz F, Otaegui D, Urcelay E, Antigüedad A, Malhotra S, Montalban X, Castillo-Triviño T, Espino-Paisán L, Aktas O, Buttmann M, Chan A, Fontaine B, Gourraud PA, Hecker M, Hoffjan S, Kubisch C, Kümpfel T, Luessi F, Zettl UK, Zipp F, Alloza I, Comabella M, Lill CM, , Vandenbroeck K, .

Journal: Cells

PubMed ID: 31936765

Doi: 10.3390/cells9010175

Products & Services: Gene Synthesis

Structure and mechanism of the ER-based glucosyltransferase ALG6

Authors: Bloch JS, Pesciullesi G, Boilevin J, Nosol K, Irobalieva RN, Darbre T, Aebi M, Kossiakoff AA, Reymond JL, Locher KP.

Journal: Nature

PubMed ID: 32103179

Doi: 10.1038/s41586-020-2044-z

Products & Services: Gene Synthesis

Rapid isothermal duplex real-time recombinase polymerase amplification (RPA) assay for the diagnosis of equine piroplasmosis

Authors: Lei R, Wang X, Zhang D, Liu Y, Chen Q, Jiang N, .

Journal: Sci Rep

PubMed ID: 32139744

Doi: 10.1038/s41598-020-60997-1

Products & Services: Gene Synthesis

Magnetic Retrieval of Encapsulated Beta Cell Transplants from Diabetic Mice Using Dual-Function MRI Visible and Retrievable Microcapsules

Authors: Delcassian D, , Luzhansky I, Spanoudaki V, Bochenek M, McGladrigan C, Nguyen A, Norcross S, Zhu Y, Shan CS, Hausser R, Shakesheff KM, Langer R, , , Anderson DG, , , .

Journal: Adv Mater

PubMed ID: 32134138

Doi: 10.1002/adma.201904502

Products & Services: Gene Synthesis

Functional Characterization of Lycopene Cyclases Illustrates the Metabolic Pathway toward Lutein in Red Algal Seaweeds

Authors: Deng YY, Cheng L, Wang Q, Ge ZH, Zheng H, Cao TJ, Lu QQ, Yang LE, Lu S.

Journal: J Agric Food Chem

PubMed ID: 31933364

Doi: 10.1021/acs.jafc.9b06918

Products & Services: Gene Synthesis

Characterization and Control of Dynamic Rearrangement in a Self-Assembled Antibody Carrier

Authors: Dhankher A, Hernandez ME, Howard HC, Champion JA.