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Consensus mutagenesis and ancestral reconstruction provide insight into the substrate specificity and evolution of the front-end Δ6-desaturase family

Authors: Dongdi Li, Adam M. Damry, James R. Petrie, Thomas Vanhercke, Surinder P. Singh, Colin J. Jackson

Journal: biorxiv

Doi: 10.1101/2020.02.07.938332

Products & Services: Gene Synthesis

Enhanced efficacy and limited systemic cytokine exposure with membrane-anchored interleukin-12 T-cell therapy in murine tumor models

Authors: Zhang L, Davies JS, Serna C, Yu Z, Restifo NP, Rosenberg SA, Morgan RA, Hinrichs CS MD

Journal: J Immunother Cancer

PubMed ID: 31959727

Doi: 10.1136/jitc-2019-000210

Products & Services: Gene Synthesis

Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

Authors: Crown A, McAlary L, Fagerli E, Brown H, Yerbury JJ, Galaleldeen A, Cashman NR, Borchelt DR, Ayers JI,

Journal: PLoS ONE

PubMed ID: 31999698

Doi: 10.1371/journal.pone.0227655

Products & Services: Gene Synthesis

Bispecific antibody approach for EGFR-directed blockade of the CD47-SIRPα "don't eat me" immune checkpoint promotes neutrophil-mediated trogoptosis and enhances antigen cross-presentation

Authors: Mark A J M Hendriks, Emily M Ploeg, Iris Koopmans, Isabel Britsch, Xiurong Ke, Douwe F Samplonius, Wijnand Helfrich

Journal: Oncoimmunology

PubMed ID: 33299654

Doi: 10.1080/2162402X.2020.1824323

Products & Services: Gene Synthesis

Generation and characterization of genetically stable heterohybridomas producing foot-and-mouth disease virus-specific porcine monoclonal antibodies

Authors: Michael C Puckette, Erica Martel, Jacob Rutherford, José Barrera, William Hurtle, Melia Pisano, Lauren Martignette, Mariceny Zurita, John G Neilan, Chungwon J Chung

Journal: J Immunol Methods

PubMed ID: 32998052

Doi: 10.1016/j.jim.2020.112873

Products & Services: Gene Synthesis

Role of YAP1 gene in proliferation, osteogenic differentiation, and apoptosis of human periodontal ligament stem cells induced by TNF-α

Authors: Tao Dong, Xuemin Sun, He Jin

Journal: J Periodontol

PubMed ID: 32997793

Doi: 10.1002/JPER.20-0176

Products & Services: Gene Synthesis

Recombinant Human Adenovirus Type 5 Co-expressing RABV G and SFTSV Gn Induces Protective Immunity Against Rabies Virus and Severe Fever With Thrombocytopenia Syndrome Virus in Mice

Authors: Zhongxin Zhao, Wenwen Zheng, Lina Yan, Peilu Sun, Tong Xu, Yelei Zhu, Lele Liu, Li Tian, Hongbin He, Yurong Wei, Xuexing Zheng

Journal: Front Microbiol

PubMed ID: 32695091

Doi: 10.3389/fmicb.2020.01473

Products & Services: Gene Synthesis

Variations of Mesozoic feathers: Insights from the morphogenesis of extant feather rachises

Authors: Shuo Wang, Wei-Ling Chang, Qiyue Zhang, Menglu Ma, Feng Yang, De Zhuo, Harn I-Chen Hans, Rui Yang, Ping Wu, Michael Habib, Wen-Tau Juan, Cheng-Ming Chuong

Journal: Evolution

PubMed ID: 32614075

Doi: 10.1111/evo.14051

Products & Services: Gene Synthesis

Methionine aminopeptidases with short sequence inserts within the catalytic domain are differentially inhibited: Structural and biochemical studies of three proteins from Vibrio spp

Authors: Vijaykumar Pillalamarri, Chilakala Gangi Reddy, Sandeep Chowdary Bala, Aruna Jangam, Vinny Vinod Kutty, Anthony Addlagatta

Journal: Eur J Med Chem

PubMed ID: 33035924

Doi: 10.1016/j.ejmech.2020.112883

Products & Services: Gene Synthesis

Biochemical characterization of ClpB3, a chloroplastic disaggregase from Arabidopsis thaliana

Authors: Ivana L Parcerisa, Germán L Rosano, Eduardo A Ceccarelli