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Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange.

Authors: Papasergi-ScottMakaía M，StovekenHannah M，MacConnachieLauren，ChanPui-Yee，GabayMeital，WongDorothy，FreemanRobert S，BegAsim A，TallGrego

Journal: Sci Signal

PubMed ID: 29844055

Doi: 10.1126/scisignal.aap8113

Products & Services: Peptide Synthesis

Computer-aided Discovery of Peptides that Specifically Attack Bacterial Biofilms.

Authors: HaneyEvan F，Brito-SánchezYoan，TrimbleMichael J，MansourSarah C，CherkasovArtem，HancockRobert

Journal: Sci Rep

PubMed ID: 29382854

Doi: 10.1038/s41598-018-19669-4

Products & Services: Peptide Synthesis

Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries.

Authors: TuckerAshley T，LeonardSean P，DuBoisCory D，KnaufGregory A，CunninghamAshley L，WilkeClaus O，TrentM Stephen，DaviesBry

Journal: Cell

PubMed ID: 29307492

Doi: 10.1016/j.cell.2017.12.009

Products & Services: Peptide Synthesis

Mitochondrial DNA is Released in Urine of SIRS Patients With Acute Kidney Injury and Correlates With Severity of Renal Dysfunction.

Authors: JansenMarcel P B，PulskensWilco P，ButterLoes M，FlorquinSandrine，JuffermansNicole P，RoelofsJoris J T H，LeemansJakli

Journal: Shock

PubMed ID: 28837526

Doi: 10.1097/SHK.0000000000000967

Products & Services: Peptide Synthesis

Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy.

Authors: SoragniElisabetta，PetrosyanLina，RinkoskiTommy A，WiebenEric D，BaratzKeith H，FautschMichael P，GottesfeldJo

Journal: Invest. Ophthalmol. Vis. Sci.

PubMed ID: 29677349

Doi: 10.1167/iovs.17-23265

Products & Services: Peptide Synthesis

TNP-470 skews DC differentiation to Th1-stimulatory phenotypes and can serve as a novel adjuvant in a cancer vaccine.

Authors: HoDerek Hoi-Hang，WongRoger Hoi-

Journal: Blood Adv

PubMed ID: 30012585

Doi: 10.1182/bloodadvances.2017013433

Products & Services: Peptide Synthesis

A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval.

Authors: KristofovaMartina，AherYogesh D，IlicMarija，RadomanBojana，KalabaPredrag，DragacevicVladimir，AherNilima Y，LebanJohann，KorzVolker，ZanonLisa，NeuhausWinfried，WiederMarcus，LangerThierry，UrbanErnst，SitteHarald H，HoegerHarald，LubecGert，Aradska

Journal: Behav. Brain Res.

PubMed ID: 29410048

Doi: 10.1016/j.bbr.2018.01.032

Products & Services: Peptide Synthesis

The EGF-LIKE domain of thrombospondin-4 is a key determinant in the development of pain states due to increased excitatory synaptogenesis.

Authors: ParkJohn Francisco，YuYanhui Peter，GongNian，TrinhVan Nancy，LuoZ D

Journal: J. Biol. Chem.

PubMed ID: 30194282

Doi: 10.1074/jbc.RA118.003591

Products & Services: Peptide Synthesis

Phosphorylation of Sox2 at Threonine 116 is a Potential Marker to Identify a Subset of Breast Cancer Cells with High Tumorigenecity and Stem-Like Features.

Authors: GuptaNidhi，GopalKeshav，WuChengsheng，AlshareefAbdulraheem，ChowAlexandra，WuFang，WangPeng，YeXiaoxia，BigrasGilbert，LaiRay