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Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.

Authors: KimMi Jin，VargasMarcelo R，HarlanBenjamin A，KilloyKelby M，BallLauren E，Comte-WaltersSusana，GoozMonika，YamamotoYasuhiko，BeckmanJoseph S，BarbeitoLuis，PeharMar

Journal: Antioxid. Redox Signal.

PubMed ID: 28537420

Doi: 10.1089/ars.2016.6966

Products & Services: Peptide Synthesis

Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.

Authors: YangWen，HsuPeter L，YangFan，SongJae-Eun，VaraniGabr

Journal: Nucleic Acids Res.

PubMed ID: 29186539

Doi: 10.1093/nar/gkx1177

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Development and performance of prototype serologic and molecular tests for hepatitis delta infection.

Authors: CollerKelly E，ButlerEmily K，LukKa-Cheung，RodgersMary A，CassidyMichael，GerschJeffrey，McNamaraAnne L，KuhnsMary C，DawsonGeorge J，KaptueLazare，BremerBirgit，WedemeyerHeiner，ClohertyGav

Journal: Sci Rep

PubMed ID: 29391553

Doi: 10.1038/s41598-018-20455-5

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Regulators of G protein Signaling (RGS) proteins promote receptor coupling to G protein-coupled inwardly-rectifying potassium (GIRK) channels.

Authors: McPhersonKylie B，LeffEmily R，LiMing-Hua，MeuriceClaire，TaiSherrica，TraynorJohn R，IngramSus

Journal: J. Neurosci.

PubMed ID: 30150362

Doi: 10.1523/JNEUROSCI.0516-18.2018

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7 H-Pyrrolo[2,3- d]pyrimidin-4-amine-Based Inhibitors of Calcium-Dependent Protein Kinase 1 Have Distinct Inhibitory and Oral Pharmacokinetic Characteristics Compared with 1 H-Pyrazolo[3,4- d]pyrimidin-4-amine-Based Inhibitors.

Authors: Rama Subba Rao Vidadala, Martin Golkowski, Matthew A. Hulverson, Ryan Choi, MollyC. McCloskey, Grant R. Whitman, Wenlin Huang, Samuel L.M. Arnold, Lynn K Barrett,Erkang Fan, Ethan A Merritt, Wesley C. Van Voorhis, Kayode K Ojo, and Dustin J Maly

Journal: ACS Infectious Diseases

Doi: 10.1021/acsinfecdis.7b00224

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The legume miR1514a modulates a NAC transcription factor transcript to trigger phasiRNA formation in response to drought

Authors: Guadalupe Sosa-Valencia, Miguel Palomar, Alejandra A. Covarrubias and José L. Reyes*

Journal: Journal of Experimental Botany, erw380.

Doi: 10.1093/jxb/erw380

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Reaching for the High Hanging Fruit: Working Towards Better Drug Discovery

Authors: Pye, Cameron

Journal: UC Santa Cruz

Doi: uc/item/85d755jc

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Targeting TNFR2 with antagonistic antibodies inhibits proliferation of ovarian cancer cells and tumor-associated Tregs

Authors: Heather Torrey, John Butterworth, Toshiyuki Mera, Yoshiaki Okubo, Limei Wang, Danielle Baum, Audrey Defusco, Sara Plager, Sarah Warden,Daniel Huang, Eva Vanamee, Rosemary Foster, Denise L. Faustman

Journal: Science Signaling

Doi: 10.1126/scisignal.aaf8608

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Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions.

Authors: Sekhar Ashok，Velyvis Algirdas，Zoltsman Guy，Rosenzweig Rina，Bouvignies Guillaume，Kay Lew

Journal: Elife

PubMed ID: 29460778

Doi: 10.7554/eLife.32764

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Pathogenic Citrulline-Multispecific B Cell Receptor Clades in Rheumatoid Arthritis.

Authors: Titcombe Philip J，Wigerblad Gustaf，Sippl Natalie，Zhang Na，Shmagel Anna K，Sahlstr?m Peter，Zhang Yue，Barsness Laura O，Ghodke-Puranik Yogita，Baharpoor Azar，Hansson Monika，Israelsson Lena，Skriner Karl，Niewold Timothy B，Klareskog Lars，Svensson Camilla I，Amara Khaled，Malmstr?m Vivianne，Mueller Dani

Journal: Arthritis Rheumatol

PubMed ID: 29927106

Doi: 10.1002/art.40590

Products & Services: Peptide Synthesis