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Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions

Authors: Arun Kumar Somavarapu, Giulia Kleijwegt, Madhu Nagaraj, Parvez Alam, Janni Nielsen, Daniel E Otzen

Journal: Chem Sci

PubMed ID: 36937574

Doi: 10.1039/d2sc05534a

Products & Services: Recombinant Proteins

A rapid nucleic acid detection platform based on phosphorothioate-DNA and sulfur binding domain

Authors: Yuting Shuai, Yi Ju, Yuanhang Li, Dini Ma, Lan Jiang, Jingyu Zhang, Gao-Yi Tan, Xueting Liu, Shenlin Wang, Lixin Zhang, Guang Liu

Journal: Synth Syst Biotechnol

PubMed ID: 36875498

Doi: 10.1016/j.synbio.2023.02.002

Products & Services: Proteins, Expression, Isolation and Analysis

Cas12a-based one-pot SNP detection with high accuracy

Authors: Hong-Xia Zhang, Caixiang Zhang, Shuhan Lu, Xiaohan Tong, Kun Zhang, Hao Yin, Ying Zhang

Journal: Cell Insight

PubMed ID: 37193068

Doi: 10.1016/j.cellin.2023.100080

Products & Services: Proteins, Expression, Isolation and Analysis

Siglec-9 Restrains Antibody-Dependent Natural Killer Cell Cytotoxicity against SARS-CoV-2

Authors: Pratima Saini, Opeyemi S Adeniji, Devivasha Bordoloi, Jennifer Kinslow, Jeff Martinson, Danielle M Parent, Kai Ying Hong, Jane Koshy, Abhijeet J Kulkarni, Netanel F Zilberstein, Robert A Balk, James N Moy, Leila B Giron, Russell P Tracy, Ali Keshavarzian, Kar Muthumani, Alan Landay, David B Weiner, Mohamed Abdel-Mohsen

Journal: MBio

PubMed ID: 36728420

Doi: 10.1128/mbio.03393-22

Products & Services: Proteins, Expression, Isolation and Analysis

Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity

Authors: Mark C Wagner, Ruben M Sandoval, Shiv Pratap S Yadav, Silvia B Campos, George J Rhodes, Carrie L Phillips, Bruce A Molitoris

Journal: Kidney360

PubMed ID: 36848531

Doi: 10.34067/KID.0000000000000094

Products & Services: Proteins, Expression, Isolation and Analysis

A biallelic loss of function variant in HORMAD1 within a large consanguineous Turkish family is associated with spermatogenic arrest

Authors: Ozlem Okutman, Manon Boivin, Jean Muller, Nicolas Charlet-Berguerand, Stéphane Viville

Journal: Hum Reprod

PubMed ID: 36524333

Doi: 10.1093/humrep/deac259

Products & Services: Proteins, Expression, Isolation and Analysis

Cathepsin H and cathepsin B of Cynoglossus semilaevis are involved in anti-bacterial immunity against Edwardsiella tarda

Authors: Yilong Wang, Hang Xu, Boguang Sun

Journal: Fish Shellfish Immunol

PubMed ID: 36754156

Doi: 10.1016/j.fsi.2023.108594

Products & Services: Proteins, Expression, Isolation and Analysis

Molecular basis of RADAR anti-phage supramolecular assemblies

Authors: Yina Gao, Xiu Luo, Peipei Li, Zhaolong Li, Feng Ye, Songqing Liu, Pu Gao

Journal: Cell

PubMed ID: 36764292

Doi: 10.1016/j.cell.2023.01.026

Products & Services: Proteins, Expression, Isolation and Analysis

Site-specific labeling of SBDS to monitor interactions with the 60S ribosomal subunit

Authors: Aparna Biswas, Yu-Fong Peng, Vikas Kaushik, Sofia Origanti

Journal: Methods

PubMed ID: 36781034

Doi: 10.1016/j.ymeth.2023.02.004

Products & Services: Proteins, Expression, Isolation and Analysis

New Monoclonal Antibodies Specific for Different Epitopes of the Spike Protein of SARS-CoV-2 and Its Major Variants: Additional Tools for a More Specific COVID-19 Diagnosis

Authors: Sabrina Mariotti, Maria Vincenza Chiantore, Raffaela Teloni, Angelo Iacobino, Antonio Capocefalo, Zuleika Michelini, Martina Borghi, Melissa Baggieri, Antonella Marchi, Paola Bucci, Silvia Gioacchini, Raffaele D'Amelio, Philip J M Brouwer, Silvia Sandini, Chiara Acchioni, Marco Sgarbanti, Antonio Di Virgilio, Felicia Grasso, Andrea Cara, Donatella Negri, Fabio Magurano, Paola Di Bonito, Roberto Nisini

Journal: Biomedicines

PubMed ID: 36831149

Doi: 10.3390/biomedicines11020610

Products & Services: Proteins, Expression, Isolation and Analysis