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Fibrotic immune microenvironment remodeling mediates superior anti-tumor efficacy of a nano-PD-L1 trap in hepatocellular carcinoma

Authors: Xiaoyu Liu, Jingying Zhou, Haoran Wu, Shufen Chen, Lingyun Zhang, Wenshu Tang, Liang Duan, Ying Wang, Eleanor McCabe, Mengying Hu, Zhuo Yu, Hanzhuang Liu, Chung Hang Jonathan Choi, Joseph Jao-Yiu Sung, Leaf Huang, Rihe Liu, Alfred Sze-Lok Cheng

Journal: Mol Ther

PubMed ID: 36146933

Doi: 10.1016/j.ymthe.2022.09.012

Products & Services: Proteins, Expression, Isolation and Analysis

Exploring the Binding Affinity and Mechanism between ACE2 and the Trimers of Delta and Omicron Spike Proteins by Molecular Dynamics Simulation and Bioassay

Authors: Liping Zhou, Tingting Liu, Mengxia Mo, Yulong Shi, Leyun Wu, Yishui Li, Qiuping Qin, Weiliang Zhu, Chengkun Wu, Likun Gong, Zhijian Xu

Journal: J Chem Inf Model

PubMed ID: 36053674

Doi: 10.1021/acs.jcim.2c00881

Products & Services: Proteins, Expression, Isolation and Analysis

Expressing the Pro-Apoptotic Reaper Protein via Insertion into the Structural Open Reading Frame of Sindbis Virus Reduces the Ability to Infect Mosquitoes

Authors: Alexis Carpenter, Scott R Santos, Rollie J Clem

Journal: Viruses

PubMed ID: 36146841

Doi: 10.3390/v14092035

Products & Services: Proteins, Expression, Isolation and Analysis

The positive regulatory loop of TCF4N/p65 promotes glioblastoma tumourigenesis and chemosensitivity

Authors: Yaling Hu, Bo Zhang, Peihua Lu, Jingying Wang, Cheng Chen, Ying Yin, Quan Wan, Jingjing Wang, Jiantong Jiao, Xiangming Fang, Zhening Pu, Lingli Gong, Li Ji, Lingpeng Zhu, Rui Zhang, Jia Zhang, Xusheng Yang, Qing Wang, Zhaohui Huang, Jian Zou

Journal: Clin Transl Med

PubMed ID: 36116131

Doi: 10.1002/ctm2.1042

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of a Potential Inhibitor (MCULE-8777613195-0-12) of New Delhi Metallo-β-Lactamase-1 (NDM-1) Using In Silico and In Vitro Approaches

Authors: Ghazala Muteeb, Md Tabish Rehman, Mohamed F AlAjmi, Mohammad Aatif, Mohd Farhan, Sheeba Shafi

Journal: Molecules

PubMed ID: 36144666

Doi: 10.3390/molecules27185930

Products & Services: Proteins, Expression, Isolation and Analysis

Context-based sensing of orthosomycin antibiotics by the translating ribosome

Authors: Kyle Mangano, James Marks, Dorota Klepacki, Chayan Kumar Saha, Gemma C Atkinson, Nora Vázquez-Laslop, Alexander S Mankin

Journal: Nat Chem Biol

PubMed ID: 36138139

Doi: 10.1038/s41589-022-01138-9

Products & Services: Proteins, Expression, Isolation and Analysis

The Pivotal Mediating Role of AMPK in Liver Tight Junctions and Liver Regeneration of a Partial-Hepatectomy Mouse Model

Authors: Xiaopeng Yan, Qinghua Shu, Liang Zhao, Bowen Sha, Yufeng Zhang

Journal: Transplant Proc

PubMed ID: 36182577

Doi: 10.1016/j.transproceed.2022.08.029

Products & Services: Proteins, Expression, Isolation and Analysis

A bHLH transcription factor, SlbHLH96, promotes drought tolerance in tomato

Authors: Yunfei Liang , Fang Ma , Boyu Li , Cong Guo , Tixu Hu , Mingke Zhang , Yan Liang , Jianhua Zhu , Xiangqiang Zhan

Journal: Hortic Res

PubMed ID: 36467272

Doi: 10.1093/hr/uhac198

Products & Services: Proteins, Expression, Isolation and Analysis

Complementary crosstalk between palmitoylation and phosphorylation events in MTIP regulates its role during invasion

Authors: Zille Anam, Geeta Kumari, Soumyadeep Mukherjee, Devasahayam Arokia Balaya Rex, Shreeja Biswas, Preeti Maurya, Susendaran Ravikumar, Nutan Gupta, Akhilesh Kumar Kushawaha, Raj Kumar Sah, Ayushi Chaurasiya, Jhalak Singhal, Niharika Singh, Shikha Kaushik, T S Keshava Prasad, Soumya Pati, Anand Ranganathan, Shailja Singh

Journal: Front Cell Infect Microbiol

PubMed ID: 36250062

Doi: 10.3389/fcimb.2022.924424

Products & Services: Recombinant Proteins

Tag-Dependent Substrate Selection of ClpX Underlies Secondary Differentiation of Chlamydia trachomatis

Authors: Nicholas A Wood, Abigail R Swoboda, Amanda M Blocker, Derek J Fisher, Scot P Ouellette

Journal: MBio

PubMed ID: 36154190

Doi: 10.1128/mbio.01858-22

Products & Services: Proteins, Expression, Isolation and Analysis