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Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects

Authors: Mohanraj Gopalswamy, Tobias Kroeger, David Bickel, Benedikt Frieg, Shahina Akter, Stephan Schott-Verdugo, Aldino Viegas, Thomas Pauly, Manuela Mayer, Julia Przibilla, Jens Reiners, Luitgard Nagel-Steger, Sander H J Smits, Georg Groth, Manuel Etzkorn, Holger Gohlke

Journal: Sci Rep

PubMed ID: 35986043

Doi: 10.1038/s41598-022-17913-6

Products & Services: Proteins, Expression, Isolation and Analysis

Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity

Authors: Yvonne Joho, Vanessa Vongsouthi, Matthew A Spence, Jennifer Ton, Chloe Gomez, Li Lynn Tan, Joe A Kaczmarski, Alessandro T Caputo, Santana Royan, Colin J Jackson, Albert Ardevol

Journal: Biochemistry

PubMed ID: 35951410

Doi: 10.1021/acs.biochem.2c00323

Products & Services: Proteins, Expression, Isolation and Analysis

Inhibitory effect of morin on aldolase 2 from Eimeria tenella

Authors: Junjing Hu, Mingfei Sun, Nanshan Qi, Asmaa M I Abuzeid, Juan Li, Haiming Cai, Minna Lv, Xuhui Lin, Shenquan Liao, Guoqing Li

Journal: Int J Parasitol Drugs Drug Resist

PubMed ID: 35952522

Doi: 10.1016/j.ijpddr.2022.07.002

Products & Services: Proteins, Expression, Isolation and Analysis

Riboflavin (Vitamin B2) Deficiency Induces Apoptosis Mediated by Endoplasmic Reticulum Stress and the CHOP Pathway in HepG2 Cells

Authors: Bo Zhang, Jun-Ting Cao, Yong-Bao Wu, Ke-Xin Gao, Ming Xie, Zheng-Kui Zhou, Jing Tang, Shui-Sheng Hou

Journal: Nutrients

PubMed ID: 36014863

Doi: 10.3390/nu14163356

Products & Services: Proteins, Expression, Isolation and Analysis

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles

Authors: Ashwanth C Francis, Anna Cereseto, Parmit K Singh, Jiong Shi, Eric Poeschla, Alan N Engelman, Christopher Aiken, Gregory B Melikyan

Journal: PLoS Pathog

PubMed ID: 35951676

Doi: 10.1371/journal.ppat.1010754

Products & Services: Proteins, Expression, Isolation and Analysis

Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene

Authors: Megan R Edwards, Olivia A Vogel, Hiroyuki Mori, Robert A Davey, Christopher F Basler

Journal: MBio

PubMed ID: 35997284

Doi: 10.1128/mbio.02243-22

Products & Services: Proteins, Expression, Isolation and Analysis

Streptococcal autolysin promotes dysfunction of swine tracheal epithelium by interacting with vimentin

Authors: Yu Meng, Qing Wang, Zhe Ma, Weiyi Li, Kai Niu, Ting Zhu, Huixing Lin, Chengping Lu, Hongjie Fan

Journal: PLoS Pathog

PubMed ID: 35921364

Doi: 10.1371/journal.ppat.1010765

Products & Services: Proteins, Expression, Isolation and Analysis

Identification of the Shigella flexneri Wzy Domain Modulating Wzz_pHS-2 Interaction and Detection of the Wzy/Wzz/Oag Complex

Authors: Alice Ascari, Elizabeth Ngoc Hoa Tran, Bart A Eijkelkamp, Renato Morona

Journal: J Bacteriol

PubMed ID: 35980183

Doi: 10.1128/jb.00224-22

Products & Services: Proteins, Expression, Isolation and Analysis

Impact of SARS-CoV-2 Spike Mutations on Its Activation by TMPRSS2 and the Alternative TMPRSS13 Protease

Authors: Annelies Stevaert, Ria Van Berwaer, Cato Mestdagh, Julie Vandeput, Els Vanstreels, Valerie Raeymaekers, Manon Laporte, Lieve Naesens

Journal: MBio

PubMed ID: 35913162

Doi: 10.1128/mbio.01376-22

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 in a Mink Farm in Italy: Case Description, Molecular and Serological Diagnosis by Comparing Different Tests

Authors: Ana Moreno, Davide Lelli, Tiziana Trogu, Antonio Lavazza, Ilaria Barbieri, MariaBeatrice Boniotti, Giulia Pezzoni, Cristian Salogni, Stefano Giovannini, Giovanni Alborali, Silvia Bellini, Massimo Boldini, Marco Farioli, Luigi Ruocco, Olivia Bessi, Andrea Maroni Ponti, Ilaria Di Bartolo, Luca De Sabato, Gabriele Vaccari, Gabriele Belli, Alberto Margutti, Maurilio Giorgi

Journal: Viruses

PubMed ID: 36016360

Doi: 10.3390/v14081738

Products & Services: Recombinant Proteins