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Condensation of the N-terminal domain of human topoisomerase 1 is driven by electrostatic interactions and tuned by its charge distribution

Authors: Greta Bianchi, Marco Mangiagalli, Diletta Ami, Junaid Ahmed, Silvia Lombardi, Sonia Longhi, Antonino Natalello, Peter Tompa, Stefania Brocca

Journal: Int J Biol Macromol

PubMed ID: 38287572

Doi: 10.1016/j.ijbiomac.2023.127754

Products & Services: Proteins, Expression, Isolation and Analysis

Unfolding of an RNA G-quadruplex motif in the negative strand genome of porcine reproductive and respiratory syndrome virus by host and viral helicases to promote viral replication

Authors: Puxian Fang, Congbao Xie, Ting Pan, Ting Cheng, Wei Chen, Sijin Xia, Tong Ding, Junkang Fang, Yanrong Zhou, Liurong Fang, Dengguo Wei, Shaobo Xiao

Journal: Nucleic Acids Res

PubMed ID: 37739415

Doi: 10.1093/nar/gkad759

Products & Services: Proteins, Expression, Isolation and Analysis

Intervention of AXL in EGFR Signaling via Phosphorylation and Stabilization of MIG6 in Non-Small Cell Lung Cancer

Authors: Ya-Yu Yang, Sheng-Chieh Lin, Jong-Ding Lay, Chun-Yu Cho, Te-Hsuan Jang, Hsiu-Ying Ku, Chih-Jung Yao, Shuang-En Chuang

Journal: Int J Mol Sci

PubMed ID: 37834326

Doi: 10.3390/ijms241914879

Products & Services: Proteins, Expression, Isolation and Analysis

A spacer design strategy for CRISPR-Cas12f1 with single-nucleotide polymorphism mutation resolution capability and its application in the mutations diagnosis of pathogens

Authors: Panqi Gao, Maoyi Yang, Yi Chen, Jun Yan, Miaomiao Han, Haijun Deng, Keli Qian, Jiandong Yang, Yaoqin Lu, Ling Zhou, Ailong Huang, Xiaosong Li, Wanyan Deng, Quanxin Long

Journal: J Med Virol

PubMed ID: 37855689

Doi: 10.1002/jmv.29189

Products & Services: Proteins, Expression, Isolation and Analysis

Vγ9+Vδ2+ T cell control of Listeria monocytogenes growth in infected epithelial cells requires butyrophilin 3A genes

Authors: Katrin Fischer, Michaela Bradlerova, Thomas Decker, Verena Supper

Journal: Sci Rep

PubMed ID: 37903831

Doi: 10.1038/s41598-023-45587-1

Products & Services: Proteins, Expression, Isolation and Analysis

Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis

Authors: Alžběta Motyčková, Luboš Voleman, Vladimíra Najdrová, Lenka Arbonová, Martin Benda, Vít Dohnálek, Natalia Janowicz, Ronald Malych, Róbert Šuťák, Thijs J G Ettema, Staffan Svärd, Courtney W Stairs, Pavel Doležal

Journal: PLoS Pathog

PubMed ID: 37792908

Doi: 10.1371/journal.ppat.1010773

Products & Services: Proteins, Expression, Isolation and Analysis

The purinergic receptor P2X7 and the NLRP3 inflammasome are druggable host factors required for SARS-CoV-2 infection

Authors: Déborah Lécuyer, Roberta Nardacci, Désirée Tannous, Emie Gutierrez-Mateyron, Aurélia Deva Nathan, Frédéric Subra, Cristina Di Primio, Paola Quaranta, Vanessa Petit, Clémence Richetta, Ali Mostefa-Kara, Franca Del Nonno, Laura Falasca, Romain Marlin, Pauline Maisonnasse, Julia Delahousse, Juliette Pascaud, Eric Deprez, Marie Naigeon, Nathalie Chaput, Angelo Paci, Véronique Saada, David Ghez, Xavier Mariette, Mario Costa, Mauro Pistello, Awatef Allouch, Olivier Delelis, Mauro Piacentini, Roger Le Grand, Jean-Luc Perfettini

Journal: Front Immunol

PubMed ID: 37920468

Doi: 10.3389/fimmu.2023.1270081

Products & Services: Proteins, Expression, Isolation and Analysis

A novel recombinant S-based subunit vaccine induces protective immunity against porcine deltacoronavirus challenge in piglets

Authors: Jizong Li, Shuqing Zhao, Baotai Zhang, Jin Huang, Qi Peng, Li Xiao, Xuesong Yuan, Rongli Guo, Jinzhu Zhou, Baochao Fan, Tao Xue, Xuejiao Zhu, Chuanmin Liu, Xing Zhu, Lili Ren, Bin Li

Journal: J Virol

PubMed ID: 37846983

Doi: 10.1128/jvi.00958-23

Products & Services: Proteins, Expression, Isolation and Analysis

Structural and dynamical changes of the Streptococcus gordonii metalloregulatory ScaR protein induced by Mn ion binding

Authors: Katarina Radman, Zoe Jelić Matošević, Dijana Žilić, Ivo Crnolatac, Nikola Bregović, Marina Kveder, Ivo Piantanida, Pedro A Fernandes, Ivana Leščić Ašler, Branimir Bertoša

Journal: Int J Biol Macromol

PubMed ID: 37866578

Doi: 10.1016/j.ijbiomac.2023.127572

Products & Services: Proteins, Expression, Isolation and Analysis

Histone Abundance Quantification via Flow Cytometry of Htb2-GFP Allows Easy Monitoring of Cell Cycle Perturbations in Living Yeast Cells, Comparable to Standard DNA Staining

Authors: Maria V Kulakova, Eslam S M O Ghazy, Fedor Ryabov, Yaroslav M Stanishevskiy, Michael O Agaphonov, Alexander I Alexandrov

Journal: J Fungi (Basel)

PubMed ID: 37888289

Doi: 10.3390/jof9101033

Products & Services: Proteins, Expression, Isolation and Analysis