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Short N-terminal disordered regions and the proline-rich domain are major regulators of phase transitions for full-length UBQLN1, UBQLN2 and UBQLN4

Authors: Thuy P Dao, Anitha Rajendran, Sarasi K K Galagedera, William Haws, Carlos A Castañeda

Journal: biorxiv

PubMed ID: 37808720

Doi: 10.1101/2023.09.27.559790

Products & Services: Proteins, Expression, Isolation and Analysis

Ultrasound-Induced Microbubble Cavitation for Targeted Delivery of MiR-29b Mimic to Treat Cardiac Fibrosis

Authors: Rafey A Feroze, Jonathan Kopechek, Jianhui Zhu, Xucai Chen, Flordeliza S Villanueva

Journal: Ultrasound Med Biol

PubMed ID: 37749011

Doi: 10.1016/j.ultrasmedbio.2023.08.025

Products & Services: Proteins, Expression, Isolation and Analysis

Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Authors: Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang

Journal: Cell Res

PubMed ID: 37674011

Doi: 10.1038/s41422-023-00870-8

Products & Services: Proteins, Expression, Isolation and Analysis

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A

Authors: Zhiheng Deng, Huasong Ai, Maoshen Sun, Zebin Tong, Yunxiang Du, Qian Qu, Liying Zhang, Ziyu Xu, Shixian Tao, Qiang Shi, Jia-Bin Li, Man Pan, Lei Liu

Journal: Mol Cell

PubMed ID: 37633270

Doi: 10.1016/j.molcel.2023.08.001

Products & Services: Proteins, Expression, Isolation and Analysis

TgLaforin, a glucan phosphatase, reveals the dynamic role of storage polysaccharides in tachyzoites and bradyzoites

Authors: Robert D Murphy, Cortni A Troublefield, Joy S Miracle, Lyndsay E A Young, Corey O Brizzee, Animesh Dhara, Ramon C Sun, Craig W Vander Kooi, Matthew S Gentry, Anthony P Sinai

Journal: biorxiv

PubMed ID: 37808860

Doi: 10.1101/2023.09.29.560185

Products & Services: Proteins, Expression, Isolation and Analysis

Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform

Authors: Ngan T B Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B H Choo, Yuansheng Yang

Journal: Sci Rep

PubMed ID: 37731040

Doi: 10.1038/s41598-023-42925-1

Products & Services: Proteins, Expression, Isolation and Analysis

Enhancing CAR T-cell Therapy Using Fab-Based Constitutively Heterodimeric Cytokine Receptors

Authors: Matteo Righi, Isaac Gannon, Matthew Robson, Saket Srivastava, Evangelia Kokalaki, Thomas Grothier, Francesco Nannini, Christopher Allen, Yuchen V Bai, James Sillibourne, Shaun Cordoba, Simon Thomas, Martin Pule

Journal: Cancer Immunol Res

PubMed ID: 37352396

Doi: 10.1158/2326-6066.CIR-22-0640

Products & Services: Proteins, Expression, Isolation and Analysis

Detection of High-Risk Paraneoplastic Antibodies against TRIM9 and TRIM67 Proteins

Authors: Christopher M Bartley, Thomas T Ngo, Le Duy Do, Anastasia Zekeridou, Ravi Dandekar, Sergio Muñiz-Castrillo, Bonny D Alvarenga, Kelsey C Zorn, Asritha Tubati, Anne-Laurie Pinto, Weston D Browne, Patrick W Hullett, Mark Terrelonge, Ryan D Schubert, Amanda L Piquet, Binxia Yang, Mayra Montalvo, Andrew F Kung, Sabrina A Mann, Maulik P Shah, Michael D Geschwind, Jeffrey M Gelfand, Joseph L DeRisi, Sean J Pittock, Jérôme Honnorat, Samuel J Pleasure, Michael R Wilson

Journal: Ann Neurol

PubMed ID: 37632288

Doi: 10.1002/ana.26776

Products & Services: Recombinant Proteins

Soluble CD4 and low molecular weight CD4-mimetic compounds sensitize cells to be killed by anti-HIV cytotoxic immunoconjugates

Authors: Seth H Pincus, Megan Stackhouse, Connie Watt, Kelli Ober, Frances M Cole, Hung-Ching Chen, Amos B Smith Iii, Tami Peters

Journal: J Virol

PubMed ID: 37772823

Doi: 10.1128/jvi.01154-23

Products & Services: Proteins, Expression, Isolation and Analysis

DSCC1 interacts with HSP90AB1 and promotes the progression of lung adenocarcinoma via regulating ER stress

Authors: Xu Lin, Ye-Han Liu, Huan-Qi Zhang, Lin-Wen Wu, Qi Li, Jun Deng, Qingyi Zhang, Yuhong Yang, Chong Zhang, Yang-Ling Li, Jian Hu