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Non-specific and specific DNA binding modes of bacterial histone, HU, separately regulate distinct physiological processes through different mechanisms
Authors: Subhash C Verma, Adam Harned, Kedar Narayan, Sankar Adhya
Journal: Mol Microbiol
PubMed ID: 36708073
Doi: 10.1111/mmi.15033
Expression, purification, and characterisation of the p53 binding domain of Retinoblastoma binding protein 6 (RBBP6)
Authors: Bonnie L Russell, Monde Ntwasa
Journal: PLoS ONE
PubMed ID: 36763571
Doi: 10.1371/journal.pone.0277478
Function of the bacteriophage P2 baseplate central spike Apex domain in the infection process
Authors: John-Mark Miller, Ekaterina S Knyazhanskaya, Sergii A Buth, Nikolai S Prokhorov, Petr G Leiman
Journal: biorxiv
PubMed ID: 36865152
Doi: 10.1101/2023.02.25.529910
A novel binary pesticidal protein from Chryseobacterium arthrosphaerae controls western corn rootworm by a different mode of action to existing commercial pesticidal proteins
Authors: Rania Jabeur, Virginie Guyon, Szabolcs Toth, Adriano E Pereira, Man P Huynh, Zakia Selmani, Erin Boland, Mickael Bosio, Laurent Beuf, Pete Clark, David Vallenet, Wafa Achouak, Carine Audiffrin, François Torney, Wyatt Paul, Thierry Heulin, Bruce E Hibbard, Stefan Toepfer, Christophe Sallaud
Journal: PLoS ONE
PubMed ID: 36800363
Doi: 10.1371/journal.pone.0267220
Mechanistic Basis for a Connection between the Catalytic Step and Slow Opening Dynamics of Adenylate Kinase
Authors: Beata Dulko-Smith, Pedro Ojeda-May, Jörgen Ådén, Magnus Wolf-Watz, Kwangho Nam
Journal: J Chem Inf Model
PubMed ID: 36802243
Doi: 10.1021/acs.jcim.2c01629
Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease
Authors: Raaj S Mehta, Jared R Mayers, Yancong Zhang, Amrisha Bhosle, Nathaniel R Glasser, Long H Nguyen, Wenjie Ma, Sena Bae, Tobyn Branck, Kijun Song, Luke Sebastian, Julian Avila Pacheco, Hyuk-Soo Seo, Clary Clish, Sirano Dhe-Paganon, Ashwin N Ananthakrishnan, Eric A Franzosa, Emily P Balskus, Andrew T Chan, Curtis Huttenhower
Journal: Nat Med
PubMed ID: 36823301
Doi: 10.1038/s41591-023-02217-7
Transplantation of A2 type astrocytes promotes neural repair and remyelination after spinal cord injury
Authors: Jie Chang, Zhanyang Qian, Binyu Wang, Jiang Cao, Sheng Zhang, Fan Jiang, Renyi Kong, Xiao Yu, Xiaojian Cao, Lei Yang, Hongtao Chen
Journal: Cell Commun Signal
PubMed ID: 36797790
Doi: 10.1186/s12964-022-01036-6
ACE2 binding and antibody evasion in enhanced transmissibility of XBB15
Authors: Can Yue, Weiliang Song, Lei Wang, Fanchong Jian, Xiaosu Chen, Fei Gao, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Yunlong Cao
Journal: Lancet Infect Dis
PubMed ID: 36746173
Doi: 10.1016/S1473-3099(23)00010-5
SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles
Authors: Ignacio A Gallardo, Daniel A Todd, Stella T Lima, Jonathan R Chekan, Norman H Chiu, Ethan Will Taylor
Journal: Antioxidants (Basel)
PubMed ID: 36978807
Doi: 10.3390/antiox12030559
Microenvironment-responsive anti-PD-L1 × CD3 bispecific T-cell engager for solid tumor immunotherapy
Authors: Dingkang Liu, Lichen Bao, Haichao Zhu, Yali Yue, Jing Tian, Xiangdong Gao, Jun Yin
Journal: Journal of controlled release
PubMed ID: 36669532
Doi: 10.1016/j.jconrel.2023.01.041
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