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Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis

Authors: Yiqi Yang , Yixuan Lin , Minqi Wang , Kai Yuan , Qishan Wang , Pei Mu , Jingke Du , Zhifeng Yu , Shengbing Yang ， Kai Huang , Yugang Wang , Hanjun Li , Tingting Tang

Journal: Bone Res

PubMed ID: 35260560

Doi: doi.org/10.1038/s41413-022-00198-w

Products & Services: Proteins, Expression, Isolation and Analysis

The vaccinia-based Sementis Copenhagen Vector coronavirus disease 2019 vaccine induces broad and durable cellular and humoral immune responses

Authors: Preethi Eldi, Tamara H Cooper, Natalie A Prow, Liang Liu, Gary K Heinemann, Voueleng J Zhang, Abigail D Trinidad, Ruth Marian Guzman-Genuino, Peter Wulff, Leanne M Hobbs, Kerrilyn R Diener, John D Hayball

Journal: Immunol Cell Biol

PubMed ID: 35188985

Doi: 10.1111/imcb.12539

Products & Services: Proteins, Expression, Isolation and Analysis

Adjusted degradation of BRD4 S and BRD4 L based on fine structural modifications of the pyrrolopyridone scaffold

Authors: Jingjing Chen, Huixin He, Aihuan Wei, Yalei Li, Gang Cheng, Hui Qin, Hanyue Zhong, Hongchun Liu, Meiyu Geng, Aijun Shen, Youhong Hu

Journal: Eur J Med Chem

PubMed ID: 35395439

Doi: 10.1016/j.ejmech.2022.114259

Products & Services: Proteins, Expression, Isolation and Analysis

Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes

Authors: Baobao Chen, Mingtian Deng, Meng-Hao Pan, Shao-Chen Sun, Honglin Liu

Journal: Cell Biosci

PubMed ID: 35255956

Doi: 10.1186/s13578-022-00758-x

Products & Services: Proteins, Expression, Isolation and Analysis

Polycystin-1 regulates cell proliferation and migration through AKT/mTORC2 pathway in a human craniosynostosis cell model

Authors: Maria A Katsianou, Kostas A Papavassiliou, Antonios N Gargalionis, George Agrogiannis, Penelope Korkolopoulou, Dimitrios Panagopoulos, Marios S Themistocleous, Christina Piperi, Efthimia K Basdra, Athanasios G Papavassiliou

Journal: J Cell Mol Med

PubMed ID: 35285136

Doi: 10.1111/jcmm.17266

Products & Services: Proteins, Expression, Isolation and Analysis

Modified vaccinia Ankara expressing EEHV1A glycoprotein B elicits humoral and cell-mediated immune responses in mice

Authors: Taylor Pursell, Jennifer L Spencer Clinton, Jie Tan, Rongsheng Peng, Paul D Ling

Journal: PLoS ONE

PubMed ID: 35312707

Doi: 10.1371/journal.pone.0265424

Products & Services: Proteins, Expression, Isolation and Analysis

Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity

Authors: Carmen Lammi, Enrico M A Fassi, Jianqiang Li, Martina Bartolomei, Giulia Benigno, Gabriella Roda, Anna Arnoldi, Giovanni Grazioso

Journal: Pharmaceutics

PubMed ID: 35336039

Doi: 10.3390/pharmaceutics14030665

Products & Services: Proteins, Expression, Isolation and Analysis

Spectrum of Phenotypic, Genetic, and Functional Characteristics in Patients With Epilepsy With Pathogenic Variants

Authors: Niklas Schwarz, Simone Seiffert, Manuela Pendziwiat, Annika Verena Rademacher, Tobias Brünger, Ulrike B S Hedrich, Paul B Augustijn, Hartmut Baier, Allan Bayat, Francesca Bisulli, Russell J Buono, Ben Zeev Bruria, Michael G Doyle, Renzo Guerrini, Gali Heimer, Michele Iacomino, Hugh Kearney, Karl Martin Klein, Ioanna Kousiappa, Wolfram S Kunz, Holger Lerche, Laura Licchetta, Ebba Lohmann, Raffaella Minardi, Marie McDonald, Sarah Montgomery, Lejla Mulahasanovic, Renske Oegema, Barel Ortal, Savvas S Papacostas, Francesca Ragona, Tiziana Granata, Phillip S Reif, Felix Rosenow, Annick Rothschild, Paolo Scudieri, Pasquale Striano, Paolo Tinuper, George A Tanteles, Annalisa Vetro, Felix Zahnert, Ethan M Goldberg, Federico Zara, Dennis Lal, Patrick May, Hiltrud Muhle, Ingo Helbig, Yvonne Weber

Journal: Neurology

PubMed ID: 35314505

Doi: 10.1212/WNL.0000000000200660

Products & Services: Proteins, Expression, Isolation and Analysis

Complement C3a Enhances the Phagocytic Activity of B Cells Through C3aR in a Fish

Authors: Zi-You Ma, Jia-Xin Liang, Wen-Shuo Li, Yuan Sun, Chang-Song Wu, Ya-Zhen Hu, Jun Li, Yong-An Zhang, Xu-Jie Zhang

Journal: Front Immunol

PubMed ID: 35386704

Doi: 10.3389/fimmu.2022.873982

Products & Services: Proteins, Expression, Isolation and Analysis

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling

Authors: Kim van Kuijk, Jasper A F Demandt, Javier Perales-Patón, Thomas L Theelen, Christoph Kuppe, Elke Marsch, Jenny de Bruijn, Han Jin, Marion J Gijbels, Ljubica Matic, Barend M E Mees, Chris P M Reutelingsperger, Ulf Hedin, Erik A L Biessen, Peter Carmeliet, Andrew H Baker, Rafael K Kramann, Leon J Schurgers, Julio Saez-Rodriguez, Judith C Sluimer

Journal: Cardiovasc Res

PubMed ID: 33913468

Doi: 10.1093/cvr/cvab152

Products & Services: Proteins, Expression, Isolation and Analysis