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IGFBP‑rP1 affects the proliferation, apoptosis and macrophage polarization of endometrial cancer cells by regulating the PI3K/AKT pathway

Authors: Juan Gao, Shiqi Suo, Jingxia Li, Chunxia Wang, Ranran Deng, Yuxia Hu, Chunzheng Zhang

Journal: Exp Ther Med

PubMed ID: 37006880

Doi: 10.3892/etm.2023.11868

Products & Services: Proteins, Expression, Isolation and Analysis

miR-126 mitigates the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting the ERK1/2 and Bcl-2 pathways

Authors: Ying Zhang, Yiping Dong, Qiushi Wei, Zhikun Zhuang, Youwen Liu, Qiang Yuan, Wei He, Zhenhao Jing, Jitian Li, Peifeng Li, Leilei Zhang, Zhinan Hong, Ning Zhang, Haibin Wang, Wuyin Li

Journal: Acta Biochim Biophys Sin (Shanghai)

PubMed ID: 36942990

Doi: 10.3724/abbs.2023016

Products & Services: Proteins, Expression, Isolation and Analysis

Immunoglobulin G subclasses confer protection against bloodstream dissemination through distinct mechanisms in mouse models

Authors: Xinhai Chen, Haley Gula, Tonu Pius, Chong Ou, Margaryta Gomozkova, Lai-Xi Wang, Olaf Schneewind, Dominique Missiakas

Journal: Proc Natl Acad Sci U S A

PubMed ID: 36972444

Doi: 10.1073/pnas.2220765120

Products & Services: Proteins, Expression, Isolation and Analysis

Arc ubiquitination regulates endoplasmic reticulum-mediated Ca release and CaMKII signaling

Authors: Mohammad A Ghane, Wei Wei, Dina W Yakout, Zachary D Allen, Cassandra L Miller, Bin Dong, Jenny J Yang, Ning Fang, Angela M Mabb

Journal: Front Cell Neurosci

PubMed ID: 36998269

Doi: 10.3389/fncel.2023.1091324

Products & Services: Proteins, Expression, Isolation and Analysis

The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function

Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, Joke Vanden Berghe, Niek Sanders, Ben Wielockx, Rudi Beyaert, Claude Libert

Journal: Front Immunol

PubMed ID: 37006237

Doi: 10.3389/fimmu.2023.1124011

Products & Services: Proteins, Expression, Isolation and Analysis

Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r

Authors: Brianne E Hoglin, Marin V Miner, Ugumuur Erbenebayar, Ciaran A Shaughnessy, Robert M Dores

Journal: Gen Comp Endocrinol

PubMed ID: 36996927

Doi: 10.1016/j.ygcen.2023.114278

Products & Services: Proteins, Expression, Isolation and Analysis

Relative role of border restrictions, case finding and contact tracing in controlling SARS-CoV-2 in the presence of undetected transmission: a mathematical modelling study

Authors: Rachael Pung, Hannah E Clapham, Timothy W Russell, Vernon J Lee, Adam J Kucharski

Journal: BMC Med

PubMed ID: 36927576

Doi: 10.1186/s12916-023-02802-0

Products & Services: Proteins, Expression, Isolation and Analysis

The proprotein convertase SKI-1/S1P is a critical host factor for Nairobi sheep disease virus infectivity

Authors: Caroline Bost, Julia Hartlaub, Vinícius Pinho Dos Reis, Thomas Strecker, Nabil G Seidah, Martin H Groschup, Sandra Diederich, Kerstin Fischer

Journal: Virus Res

PubMed ID: 36948228

Doi: 10.1016/j.virusres.2023.199099

Products & Services: Proteins, Expression, Isolation and Analysis

Rare Catechol--methyltransferase Missense Variants Are Structurally Unstable Proteasome Targets

Authors: Fia B Larsen, Matteo Cagiada, Jonas Dideriksen, Amelie Stein, Kresten Lindorff-Larsen, Rasmus Hartmann-Petersen

Journal: Biochemistry

PubMed ID: 36976271

Doi: 10.1021/acs.biochem.3c00008

Products & Services: Proteins, Expression, Isolation and Analysis

Nanotopographic micro-nano forces finely tune the conformation of macrophage mechanosensitive membrane protein integrin β to manipulate inflammatory responses

Authors: Yuanlong Guo, Yong Ao, Chen Ye, Ruidi Xia, Jiaomei Mi, Zhengjie Shan, Mengru Shi, Lv Xie, Zetao Chen