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Extracellular expression of 's L-asparaginase II in results in novel enzyme with better parameters

Authors: Henrique P Biasoto, Cristina B Hebeda, Sandra H P Farsky, Adalberto Pessoa, Tales A Costa-Silva, Gisele Monteiro

Journal: Prep Biochem Biotechnol

PubMed ID: 35981094

Doi: 10.1080/10826068.2022.2111582

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Safety and Immunogenicity of an Inactivated Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine in a Subgroup of Healthy Adults in Chile

Authors: Susan M Bueno, Katia Abarca, Pablo A González, Nicolás M S Gálvez, Jorge A Soto, Luisa F Duarte, Bárbara M Schultz, Gaspar A Pacheco, Liliana A González, Yaneisi Vázquez, Mariana Ríos, Felipe Melo-González, Daniela Rivera-Pérez, Carolina Iturriaga, Marcela Urzúa, Angélica Domínguez, Catalina A Andrade, Roslye V Berríos-Rojas, Gisela Canedo-Marroquín, Camila Covián, Daniela Moreno-Tapia, Farides Saavedra, Omar P Vallejos, Paulina Donato, Pilar Espinoza, Daniela Fuentes, Marcela González, Paula Guzmán, Paula Muñoz Venturelli, Carlos M Pérez, Marcela Potin, Álvaro Rojas, Rodrigo A Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Aarón Oyarzún-Arrau, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alessandro Sette, Gang Zeng, Weining Meng, José V González-Aramundiz, Alexis M Kalergis

Journal: Clin Infect Dis

PubMed ID: 34537835

Doi: 10.1093/cid/ciab823

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Discovery and identification of a novel small molecule BCL-2 inhibitor that binds to the BH4 domain

Authors: Jing-Yi Zhou, Rui-Rui Yang, Jie Chang, Jia Song, Zi-Sheng Fan, Ying-Hui Zhang, Cheng-Hao Lu, Hua-Liang Jiang, Ming-Yue Zheng, Su-Lin Zhang

Journal: Acta Pharmacol Sin

PubMed ID: 35918411

Doi: 10.1038/s41401-022-00936-0

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Sall4 guides p53-mediated enhancer interference upon DNA damage in mouse embryonic stem cells

Authors: Lei Wang, Xiaojun Tan, Lu Chen, Sisi Xu, Weiping Huang, Nan Chen, Yizhou Wu, Chunyan Wang, Daqiang Zhou, Mangmang Li

Journal: Stem Cells

PubMed ID: 35977539

Doi: 10.1093/stmcls/sxac058

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Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses

Authors: Jeroen M J Tas, Ja-Hyun Koo, Ying-Cing Lin, Zhenfei Xie, Jon M Steichen, Abigail M Jackson, Blake M Hauser, Xuesong Wang, Christopher A Cottrell, Jonathan L Torres, John E Warner, Kathrin H Kirsch, Stephanie R Weldon, Bettina Groschel, Bartek Nogal, Gabriel Ozorowski, Sandhya Bangaru, Nicole Phelps, Yumiko Adachi, Saman Eskandarzadeh, Michael Kubitz, Dennis R Burton, Daniel Lingwood, Aaron G Schmidt, Usha Nair, Andrew B Ward, William R Schief, Facundo D Batista

Journal: Immunity

PubMed ID: 35987201

Doi: 10.1016/j.immuni.2022.07.020

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Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency

Authors: Zhipeng Ai, Xinyu Xiang, Yangquan Xiang, Iwona Szczerbinska, Yuli Qian, Xiao Xu, Chenyang Ma, Yaqi Su, Bing Gao, Hao Shen, Muhammad Nadzim Bin Ramli, Di Chen, Yue Liu, Jia-Jie Hao, Huck Hui Ng, Dan Zhang, Yun-Shen Chan, Wanlu Liu, Hongqing Liang

Journal: Cell Rep

PubMed ID: 36001968

Doi: 10.1016/j.celrep.2022.111240

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Dynamicity and persistence of severe acute respiratory syndrome coronavirus-2 antibody response after double dose and the third dose with BBV-152 and AZD1222 vaccines: A prospective, longitudinal cohort study

Authors: Debaprasad Parai, Hari Ram Choudhary, Girish Chandra Dash, Susmita Behera, Narayan Mishra, Dipti Pattnaik, Sunil Kumar Raghav, Sanjeeb Kumar Mishra, Subrat Kumar Sahoo, Aparajita Swain, Ira Mohapatra, Matrujyoti Pattnaik, Aparnamayee Moharana, Sandhya Rani Jena, Ira Praharaj, Subhra Subhadra, Srikanta Kanungo, Debdutta Bhattacharya, Sanghamitra Pati

Journal: Front Microbiol

PubMed ID: 36016787

Doi: 10.3389/fmicb.2022.942659

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Induction of Defense Responses and Protection of Almond Plants Against by Endotherapy with a Bifunctional Peptide

Authors: Luís Moll, Aina Baró, Laura Montesinos, Esther Badosa, Anna Bonaterra, Emilio Montesinos

Journal: Phytopathology

PubMed ID: 35384723

Doi: 10.1094/PHYTO-12-21-0525-R

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ChAdOx1 nCoV-19 (AZD1222) or nCoV-19-Beta (AZD2816) protect Syrian hamsters against Beta Delta and Omicron variants

Authors: Neeltje van Doremalen, Jonathan E Schulz, Danielle R Adney, Taylor A Saturday, Robert J Fischer, Claude Kwe Yinda, Nazia Thakur, Joseph Newman, Marta Ulaszewska, Sandra Belij-Rammerstorfer, Greg Saturday, Alexandra J Spencer, Dalan Bailey, Colin A Russell, Sarah C Gilbert, Teresa Lambe, Vincent J Munster

Journal: Nat Commun

PubMed ID: 35941149

Doi: 10.1038/s41467-022-32248-6

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Permissive omicron breakthrough infections in individuals with binding or neutralizing antibodies to ancestral SARS-CoV-2

Authors: Erin Williams, Jordan Colson, Ranjini Valiathan, Juan Manuel Carreño, Florian Krammer, Michael Hoffer, Suresh Pallikkuth, Savita Pahwa, David Andrews

Journal: Vaccine

PubMed ID: 36088193

Doi: 10.1016/j.vaccine.2022.08.058

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