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至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

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ATOR-1017 (evunzekibart), an Fc-gamma receptor conditional 4-1BB agonist designed for optimal safety and efficacy, activates exhausted T cells in combination with anti-PD-1

Authors: Karin Enell Smith, Sara Fritzell, Anneli Nilsson, Karin Barchan, Anna Rosén, Lena Schultz, Laura Varas, Anna Säll, Nadia Rose, Maria Håkansson, Laura von Schantz, Peter Ellmark

Journal: Cancer Immunol Immunother

PubMed ID: 37796298

Doi: 10.1007/s00262-023-03548-7

Products & Services: Gene Synthesis

Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics

Authors: Katarzyna Pustelny, Przemyslaw Grygier, Agata Barzowska, Barbara Pucelik, Alex Matsuda, Krzysztof Mrowiec, Emilia Slugocka, Grzegorz M Popowicz, Grzegorz Dubin, Anna Czarna

Journal: Sci Rep

PubMed ID: 37872245

Doi: 10.1038/s41598-023-44810-3

Products & Services: Plasmid DNA Preparation

β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor

Authors: Carole Daly, Akim Abdul Guseinov, Hyunggu Hahn, Adam Wright, Irina G Tikhonova, Alex Rojas Bie Thomsen, Bianca Plouffe

Journal: Elife

PubMed ID: 37855711

Doi: 10.7554/eLife.87754

Products & Services: PCR Cloning and Subcloning

Opsin 5 mediates violet light-induced early growth response-1 expression in the mouse retina

Authors: Heonuk Jeong, Deokho Lee, Xiaoyan Jiang, Kazuno Negishi, Kazuo Tsubota, Toshihide Kurihara

Journal: Sci Rep

PubMed ID: 37857760

Doi: 10.1038/s41598-023-44983-x

Products & Services: Gene Synthesis

Rapamycin nanoparticles increase the therapeutic window of engineered interleukin-2 and drive expansion of antigen-specific regulatory T cells for protection against autoimmune disease

Authors: Takashi Kei Kishimoto, Max Fournier, Alicia Michaud, Gina Rizzo, Christopher Roy, Teresa Capela, Natasha Nukolova, Ning Li, Liam Doyle, Fen-Ni Fu, Derek VanDyke, Peter G Traber, Jamie B Spangler, Sheldon S Leung, Petr O Ilyinskii

Journal: J Autoimmun

PubMed ID: 37844543

Doi: 10.1016/j.jaut.2023.103125

Products & Services: Proteins, Expression, Isolation and Analysis

Selection, activity, and nuclease stabilization of cross-neutralizing DNA aptamers targeting HSV-1 and HSV-2

Authors: Michael D Schump, David I Bernstein, Fernando J Bravo, Charles P Neff

Journal: Virology

PubMed ID: 37925791

Doi: 10.1016/j.virol.2023.109916

Products & Services: Molecular Biology Reagents

Aptabinding of tumor necrosis factor-α (TNFα) inhibits its proinflammatory effects and alleviates islet inflammation

Authors: Roaa Mahmoud, Jagan Kalivarathan, Abdul J Castillo, Sasha Wang, Brian Fuglestad, Mazhar A Kanak, Soma Dhakal

Journal: Biotechnol J

PubMed ID: 37772688

Doi: 10.1002/biot.202300374

Products & Services: Molecular Biology Reagents

GhL1L1 regulates the contents of unsaturated fatty acids by activating the expression of GhFAD2 genes in cotton

Authors: Dandan Yue, Xuyang Hao, Bei Han, Jiao Xu, Weinan Sun, Xiaoping Guo, Xianlong Zhang, Xiyan Yang

Journal: Gene

PubMed ID: 37839764

Doi: 10.1016/j.gene.2023.147899

Products & Services: PCR Cloning and Subcloning

A newly identified ferritin L-subunit variant results in increased proteasomal subunit degradation, impaired complex assembly, and severe hypoferritinemia

Authors: Dayana Shagidov, Noga Guttmann-Raviv, Séverine Cunat, Liora Frech, Muriel Giansily-Blaizot, Niraj Ghatpande, Gili Abelya, Gabriel A Frank, Patricia Aguilar Martinez, Esther G Meyron-Holtz

Journal: Am J Hematol

PubMed ID: 37867341

Doi: 10.1002/ajh.27124

Products & Services: Proteins, Expression, Isolation and Analysis

Characterization of a thermostable Cas12a ortholog

Authors: Jing Wu, Pan Gao, Yajing Shi, Caixiang Zhang, Xiaohan Tong, Huidi Fan, Xi Zhou, Ying Zhang, Hao Yin

Journal: Cell Insight

PubMed ID: 38047138

Doi: 10.1016/j.cellin.2023.100126

Products & Services: Molecular Biology Reagents