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C-IGF1R encoded by cIGF1R acts as a molecular switch to restrict mitophagy of drug-tolerant persister tumour cells in non-small cell lung cancer

Authors: Hui Wang, Yingkuan Liang, Te Zhang, Xinnian Yu, Xuming Song, Yuzhong Chen, Qixing Mao, Wenjie Xia, Bing Chen, Lin Xu, Gaochao Dong, Feng Jiang

Journal: Cell Death Differ

PubMed ID: 37689814

Doi: 10.1038/s41418-023-01222-0

Products & Services: Custom RNAi Services

Cryo-EM structures of human organic anion transporting polypeptide OATP1B1

Authors: Ziyang Shan, Xuemei Yang, Huihui Liu, Yafei Yuan, Yuan Xiao, Jing Nan, Wei Zhang, Wenqi Song, Jufang Wang, Feiwen Wei, Yanqing Zhang

Journal: Cell Res

PubMed ID: 37674011

Doi: 10.1038/s41422-023-00870-8

Products & Services: Proteins, Expression, Isolation and Analysis

Refactoring the architecture of a polyketide gene cluster enhances docosahexaenoic acid production in Yarrowia lipolytica through improved expression and genetic stability

Authors: Demian Dietrich, Sofija Jovanovic-Gasovic, Peng Cao, Michael Kohlstedt, Christoph Wittmann

Journal: Microb Cell Fact

PubMed ID: 37773137

Doi: 10.1186/s12934-023-02209-9

Products & Services: Catalog Peptides

Bispecific antibody CD73xEGFR more selectively inhibits the CD73/adenosine immune checkpoint on cancer cells and concurrently counteracts pro-oncogenic activities of CD73 and EGFR

Authors: Emily Maria Ploeg , Douwe Freerk Samplonius, Xiao Xiong , Xiurong Ke, Mark Alexander Johannes Martinus Hendriks , Isabel Britsch , Anne Paulien van Wijngaarden , Hao Zhang , Wijnand Helfrich

Journal: J Immunother Cancer .

PubMed ID: 37734877

Doi: 10.1136/jitc-2023-006837

Products & Services: Gene Synthesis

Glycoengineering directs de novo biomanufacturing of UPEC O21 O-antigen polysaccharide based glycoprotein

Authors: Yuhui Wang , Andrei V Perepelov , Sof'ya N Senchenkova , Gege Lu , Xiaohan Wang , Guozhen Ma , Qian Yang , Jian Yuan , Yanling Wang , Lijie Xie , Xiaolong Jiang , Jingliang Qin , Dan Liu , Miaomiao Liu , Di Huang , Bin Liu

Journal: Int J Biol Macromol .

PubMed ID: 37739281

Doi: 10.1016/j.ijbiomac.2023.126993

Products & Services: Proteins, Expression, Isolation and Analysis

Photoactivated DNA Nanodrugs Damage Mitochondria to Improve Gene Therapy for Reversing Chemoresistance

Authors: Danyu Wang , Hua Yi , Shizhen Geng , Chuanmei Jiang , Jingwen Liu , Jie Duan , Zhenzhong Zhang, Jinjin Shi , Haiwei Song , Zhenzhen Guo, Kaixiang Zhang

Journal: ACS Nano .

PubMed ID: 37606317

Doi: 10.1021/acsnano.3c04002

Products & Services: Catalog Antibody

Validation of flavivirus infectious clones carrying fluorescent markers for antiviral drug screening and replication studies

Authors: Liubov Cherkashchenko , Nathalie Gros, Alice Trausch, Aymeric Neyret, Mathilde Hénaut, Gregor Dubois, Matthieu Villeneuve, Christine Chable-Bessia, Sébastien Lyonnais, Andres Merits, Delphine Muriaux

Journal: Front Microbiol

PubMed ID: 37779700

Doi: 10.3389/fmicb.2023.1201640

Products & Services: Gene Synthesis

Optimizing effector functions of monoclonal antibodies via tailored N-glycan engineering using a dual landing pad CHO targeted integration platform

Authors: Ngan T B Nguyen, Hau Wan Leung, Kuin Tian Pang, Shi Jie Tay, Ian Walsh, Andre B H Choo, Yuansheng Yang

Journal: Sci Rep

PubMed ID: 37731040

Doi: 10.1038/s41598-023-42925-1

Products & Services: Proteins, Expression, Isolation and Analysis

The Dictyostelium discoideum FimA protein, unlike yeast and plant fimbrins, is regulated by calcium similar to mammalian plastins

Authors: Hiroaki Ishida, Andrew G Woodman, Naoya Kitada, Tomoyasu Aizawa, Hans J Vogel