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A model of human neural networks reveals NPTX2 pathology in ALS and FTLD
Authors: Marian Hruska-Plochan, Vera I Wiersma, Katharina M Betz, Izaskun Mallona, Silvia Ronchi, Zuzanna Maniecka, Eva-Maria Hock, Elena Tantardini, Florent Laferriere, Sonu Sahadevan, Vanessa Hoop, Igor Delvendahl, Manuela Pérez-Berlanga, Beatrice Gatta, Martina Panatta, Alexander van der Bourg, Dasa Bohaciakova, Puneet Sharma , Laura De Vos, Karl Frontzek , Adriano Aguzzi, Tammaryn Lashley , Mark D Robinson, Theofanis Karayannis, Martin Mueller, Andreas Hierlemann 4, Magdalini Polymenidou 13
Journal: Nature
PubMed ID: 38355792
Doi: 10.1038/s41586-024-07042-7
Products & Services: Gene Synthesis   
Ribosomal collision is not a prerequisite for ZNF598-mediated ribosome ubiquitination and disassembly of ribosomal complexes by ASCC
Authors: Anna Miścicka, Alexander G Bulakhov, Kazushige Kuroha, Alexandra Zinoviev, Christopher U T Hellen, Tatyana V Pestova
Journal: Nucleic Acids Res
PubMed ID: 38366554
Doi: 10.1093/nar/gkae087
Products & Services: Custom Vector Construction   
Molecular mechanism of human ISG20L2 for the ITS1 clea vag e in the processing of 18S precursor ribosomal RNA
Authors: Yinliang Ma, Jiaxu Wang, Xingyi He, Yuhang Liu, Shuo Zhen, Lina An, Qian Yang, Fumin Niu, Hong Wang, Boran An, Xinyue Tai, Zhenzhen Yan, Chen Wu, Xiaoyun Yang, Xiuhua Liu
Journal: Nucleic Acids Res
PubMed ID: 38153123
Doi: 10.1093/nar/gkad1210
Products & Services: Gene Synthesis   
Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel Na18 with a Unique Mechanism of Action
Authors: John M Gilchrist, Nien-Du Yang, Victoria Jiang, Bryan D Moyer
Journal: Mol Pharmacol
PubMed ID: 38195157
Doi: 10.1124/molpharm.123.000789
Products & Services: Mutagenesis Services   
The ETI-dependent receptor-like kinase 1 positively regulates effector-triggered immunity by stabilizing NLR-required for cell death 4 in Nicotiana benthamiana
Authors: Yujing Sun, Fan Liu, Mengzhu Zeng, Xinjie Zhang, Ying Cui, Zhaodan Chen, Lei Wang, Yuanpeng Xu, Jinbin Wu, Shengya Guo, Xian Dong, Suomeng Dong, Yan Wang, Yuanchao Wang
Journal: New Phytol
PubMed ID: 38362937
Doi: 10.1111/nph.19596
Products & Services: DNA Sequencing   
Safety and immunogenicity of CoronaVac in healthy adults: A prospective observational multicenter real-world study in Henan Province, China
Authors: Benchen Rao, Ling Wang, Mengzhao Yang, Hong Luo, Junyi Sun, Shanshuo Liu, Haiyu Wang, Xuemei Wang, Lei Li, Chengyu Yuan, Zujiang Yu, Zhigang Ren
Journal: Virulence
PubMed ID: 38326274
Doi: 10.1080/21505594.2024.2310450
Products & Services: Molecular Biology Reagents   
DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α
Authors: Aidi Gao, Mingxia Zhang, Shuang Qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao
Journal: Cell Death Dis
PubMed ID: 38402183
Doi: 10.1038/s41419-024-06552-6
Progranulin haploinsufficiency mediates cytoplasmic TDP-43 aggregation with lysosomal abnormalities in human microglia
Authors: Wonjae Sung, Min-Young Noh, Minyeop Nahm, Yong Sung Kim, Chang-Seok Ki, Young-Eun Kim, Hee-Jin Kim, Seung Hyun Kim
Journal: J Neuroinflammation
PubMed ID: 38347588
Doi: 10.1186/s12974-024-03039-1
Products & Services: Gene Synthesis   
Ultrasound Imaging of Tumor Vascular CD93 with MMRN2 Modified Microbubbles for Immune Microenvironment Prediction
Authors: Dingyi Wang, Changyang Xing, Yuan Liang, Chen Wang, Ping Zhao, Xiao Liang, Qiuyang Li, Lijun Yuan
Journal: Adv Mater
PubMed ID: 38270289
Doi: 10.1002/adma.202310421
Products & Services: Molecular Biology Reagents   
Structural and mechanistic characterization of bifunctional heparan sulfate N-deacetylase-N-sulfotransferase 1
Authors: Courtney J Mycroft-West, Sahar Abdelkarim, Helen M E Duyvesteyn, Neha S Gandhi, Mark A Skidmore, Raymond J Owens, Liang Wu
Journal: Nat Commun
PubMed ID: 38351061
Doi: 10.1038/s41467-024-45419-4
Products & Services: Molecular Biology Reagents   

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