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Amyloidogenic propensity of self-assembling peptides and their adjuvant potential for use as DNA vaccines

Authors: Paresh C Shrimali, Sheng Chen, Anirban Das, Rachel Dreher, Matthew K Howard, Jeremy J Ryan, Jeremy Buck, Darren Kim, Macy L Sprunger, Jai S Rudra, Meredith E Jackrel

Journal: Acta Biomater

PubMed ID: 37586449

Doi: 10.1016/j.actbio.2023.08.015

Products & Services: Proteins, Expression, Isolation and Analysis

SARS-CoV-2 fusion peptide sculpting of a membrane with insertion of charged and polar groups

Authors: Steven R Van Doren, Benjamin S Scott, Rama K Koppisetti

Journal: Structure

PubMed ID: 37625399

Doi: 10.1016/j.str.2023.07.015

Products & Services: Proteins, Expression, Isolation and Analysis

Brain-Derived 11S Regulator (PA28αβ) Promotes Proteasomal Hydrolysis of Elongated Oligoglutamine-Containing Peptides

Authors: Viacheslav A Kriachkov, Natalia N Gotmanova, Vadim N Tashlitsky, Anna V Bacheva

Journal: Int J Mol Sci

PubMed ID: 37686081

Doi: 10.3390/ijms241713275

Products & Services: Peptide Synthesis

Iguratimod attenuated fibrosis in systemic sclerosis via targeting early growth response 1 expression

Authors: Lichong Shen, Hanlin Yin, Li Sun, Zhiliang Zhang, Yuyang Jin, Shan Cao, Qiong Fu, Chaofan Fan, Chunde Bao, Liangjing Lu, Yifan Zhan, Xiaojiang Xu, Xiaoxiang Chen, Qingran Yan

Journal: Arthritis Res Ther

PubMed ID: 37596660

Doi: 10.1186/s13075-023-03135-2

Products & Services: Molecular Biology Reagents

Newcastle disease virus (NDV) recombinant expressing Marek's disease virus (MDV) glycoprotein B significantly protects chickens against MDV and NDV challenges

Authors: Lei He, Stephen Spatz, John R Dunn, Qingzhong Yu

Journal: Vaccine

PubMed ID: 37598026

Doi: 10.1016/j.vaccine.2023.08.038

Products & Services: Molecular Biology Reagents

Extended-Gate Field-Effect Transistor Consisted of a CD9 Aptamer and MXene for Exosome Detection in Human Serum

Authors: Jeongyun An, Hyunjun Park, Jinmyeong Kim, Hanbin Park, Tae-Hyung Kim, Chulhwan Park, Jeonghyun Kim, Min-Ho Lee, Taek Lee

Journal: ACS Sens

PubMed ID: 37585601

Doi: 10.1021/acssensors.3c00879

Products & Services: Proteins, Expression, Isolation and Analysis

Rapid and Sensitive Diagnosis of Leber Hereditary Optic Neuropathy Variants Using CRISPR/Cas12a Detection

Authors: Xiaoling Wan, Jieqiong Chen, Yidong Wu, Zhixuan Chen, Yin Liu, Tong Li, Junran Sun, Ting Zhang, Fuling Zhou, Xingxu Huang, Yang Li, Xinjie Wang, Xiaodong Sun

Journal: J Mol Diagn

PubMed ID: 37517824

Doi: 10.1016/j.jmoldx.2023.04.006

Products & Services: Custom DNA/RNA Oligos

Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif

Authors: Peter Schofield, Alexander I Taylor, Jérôme Rihon, Cristian D Peña Martinez, Sacha Zinn, Charles-Alexandre Mattelaer, Jennifer Jackson, Gurpreet Dhaliwal, Guy Schepers, Piet Herdewijn, Eveline Lescrinier, Daniel Christ, Philipp Holliger

Journal: Nucleic Acids Res

PubMed ID: 37439359

Doi: 10.1093/nar/gkad592

Products & Services: Gene Synthesis

Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells

Authors: Kevin M Rattigan, Zuzana Brabcova, Daniele Sarnello, Martha M Zarou, Kiron Roy, Ryan Kwan, Lucie de Beauchamp, Amy Dawson, Angela Ianniciello, Ahmed Khalaf, Eric R Kalkman, Mary T Scott, Karen Dunn, David Sumpton, Alison M Michie, Mhairi Copland, Saverio Tardito, Eyal Gottlieb, G Vignir Helgason

Journal: Nat Commun

PubMed ID: 37591854

Doi: 10.1038/s41467-023-40222-z

Products & Services: Custom DNA/RNA Oligos

Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily

Authors: Fenglian Liu, Yu Dang, Lu Li, Hao Feng, Jianlin Li, Haowei Wang, Xu Zhang, Zhe Zhang, Sheng Ye, Yutao Tian, Qingfeng Chen

Journal: Nat Chem Biol

PubMed ID: 37550431

Doi: 10.1038/s41589-023-01401-7

Products & Services: Peptide Synthesis