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Glyoxylate reductase: Definitive identification in human liver mitochondria, its importance for the compartment-specific detoxification of glyoxylate

Authors: Sander F Garrelfs, Serhii Chornyi, Heleen Te Brinke, Jos Ruiter, Jaap Groothoff, Ronald J A Wanders

Journal: J Inherit Metab Dis

PubMed ID: 38200664

Doi: 10.1002/jimd.12711

Products & Services: Gene Synthesis

Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer

Authors: Giuseppe Rospo, Rosaria Chilà, Vittoria Matafora, Veronica Basso, Simona Lamba, Alice Bartolini, Angela Bachi, Federica Di Nicolantonio, Anna Mondino, Giovanni Germano, Alberto Bardelli

Journal: Genome Med

PubMed ID: 38243308

Doi: 10.1186/s13073-023-01275-3

Products & Services: Proteins, Expression, Isolation and Analysis

Hepatitis C virus E1 recruits high-density lipoprotein to support infectivity and evade antibody recognition

Authors: Jennifer Casiano Matos, Kaneemozhe Harichandran, Jingrong Tang, Denis O Sviridov, Giacomo Sidoti Migliore, Motoshi Suzuki, Lisa R Olano, Alvaro Hobbs, Ashish Kumar, Myeisha U Paskel, Mattia Bonsignori, Altaira D Dearborn, Alan T Remaley, Joseph Marcotrigiano

Journal: J Virol

PubMed ID: 38174935

Doi: 10.1128/jvi.00849-23

Products & Services: Proteins, Expression, Isolation and Analysis

The lncRNA HCG4 regulates the RIG-I-mediated IFN production to suppress H1N1 swine influenza virus replication

Authors: Jinghua Cheng, Jie Tao, Benqiang Li, Ying Shi, Huili Liu

Journal: Front Microbiol

PubMed ID: 38274760

Doi: 10.3389/fmicb.2023.1324218

Products & Services: Proteins, Expression, Isolation and Analysis

Predicting multiple conformations via sequence clustering and AlphaFold2

Authors: Hannah K Wayment-Steele, Adedolapo Ojoawo, Renee Otten, Julia M Apitz, Warintra Pitsawong, Marc Hömberger, Sergey Ovchinnikov, Lucy Colwell, Dorothee Kern

Journal: Nature

PubMed ID: 37956700

Doi: 10.1038/s41586-023-06832-9

Products & Services: Custom Vector Construction

N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting

Authors: Thomas E Mulroney, Tuija Pöyry, Juan Carlos Yam-Puc, Maria Rust, Robert F Harvey, Lajos Kalmar, Emily Horner, Lucy Booth, Alexander P Ferreira, Mark Stoneley, Ritwick Sawarkar, Alexander J Mentzer, Kathryn S Lilley, C Mark Smales, Tobias von der Haar, Lance Turtle, Susanna Dunachie, Paul Klenerman, James E D Thaventhiran, Anne E Willis

Journal: Nature

PubMed ID: 38057663

Doi: 10.1038/s41586-023-06800-3

Products & Services: PCR Cloning and Subcloning

Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

Authors: Rajeshwer S Sankhala , Kerri G Lal , Jaime L Jensen , Vincent Dussupt , Letzibeth Mendez-Rivera , Hongjun Bai , Lindsay Wieczorek , Sandra V Mayer , Michelle Zemil , Danielle A Wagner , Samantha M Townsley , Agnes Hajduczki , William C Chang , Wei-Hung Chen , Gina C Donofrio , Ningbo Jian , Hannah A D King , Cynthia G Lorang , Elizabeth J Martinez , Phyllis A Rees , Caroline E Peterson , Fabian Schmidt , Tricia J Hart , Debra K Duso , Lawrence W Kummer , Sean P Casey , Jazmean K Williams , Shruthi Kannan , Bonnie M Slike , Lauren Smith , Isabella Swafford , Paul V Thomas , Ursula Tran , Jeffrey R Currier , Diane L Bolton , Edgar Davidson , Benjamin J Doranz , Theodora Hatziioannou , Paul D Bieniasz , Dominic Paquin-Proulx , William W Reiley , Morgane Rolland , Nancy J Sullivan , Sandhya Vasan , Natalie D Collins , Kayvon Modjarrad , Gregory D Gromowski , Victoria R Polonis , Nelson L Michael , Shelly J Krebs , M Gordon Joyce

Journal: Nat Commun

PubMed ID: 38172512

Doi: 10.1038/s41467-023-44265-0.

Products & Services: Antibody Modification and Purification Services

Therapeutic vaccination with lentiviral vector in HBV-persistent mice and two inactive HBsAg carriers

Authors: Yumeng Zhang, Maryline Bourgine , Yanmin Wan, Jieyu Song, Zongying Li, Yiqi Yu, Wangfang Jiang, Mingzhe Zhou, Cuiyuan Guo, Didier Santucci, Xiao Liang, Christian Brechot, Wenhong Zhang, Pierre Charneau, Hong Wu, Chao Qiu

Journal: Hepatology

PubMed ID: 37827470

Doi: 10.1016/j.jhep.2023.09.019

Products & Services: Peptide Synthesis

A new antibiotic traps lipopolysaccharide in its intermembrane transporter

Authors: Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth Bradley, Andrew C Kruse 4, Daniel Kahne 5

Journal: Nature

PubMed ID: 38172635

Doi: 10.1038/s41586-023-06799-7

Products & Services: Peptide Synthesis

Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Authors: Jason Z. Zhang, William H. Nguyen, Nathan Greenwood, John C. Rose, Shao-En Ong, Dustin J. Maly & David Baker

Journal: Nature Biotechnol

PubMed ID: 38228150

Doi: 10.1038/s41587-023-02107-w

Products & Services: Plasmid DNA Preparation