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Cognitive impairment is associated with BDNF-TrkB signaling mediating synaptic damage and reduction of amino acid neurotransmitters in heart failure

Authors: Lei Wang, Ziwen Lu, Yu Teng, Weibing Pan, Yang Li, Sha Su, Jingling Chang, Mingjing Zhao

Journal: FASEB J

PubMed ID: 38085181

Doi: 10.1096/fj.202301699RR

Products & Services: Proteins, Expression, Isolation and Analysis

Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

Authors: Chia Ying Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 38289714

Doi: 10.1107/S2059798324000329

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis of prostaglandin efflux by MRP4

Authors: Sergei Pourmal, Evan Green, Ruchika Bajaj, Ilan E Chemmama, Giselle M Knudsen, Meghna Gupta, Andrej Sali, Yifan Cheng, Charles S Craik, Deanna L Kroetz, Robert M Stroud

Journal: Nat Struct Mol Biol

PubMed ID: 38216659

Doi: 10.1038/s41594-023-01176-4

Products & Services: Mutant Libraries

Beta-1,3-Glucan-Binding Protein Inhibits Dengue and ZIKA Virus Replication

Authors: Xiaoxue Xie, Di Wang, Bo Li, Guorui Liang, Xiaoli Chen, Dan Xing, Teng Zhao, Xinyu Zhou, Chunxiao Li

Journal: Biomedicines

PubMed ID: 38255195

Doi: 10.3390/biomedicines12010088

Products & Services: DNA Sequencing

Increasing the Pentose Phosphate Pathway Flux to Improve Plasmid DNA Production in Engineered

Authors: Mitzi de la Cruz, Flavio Kunert, Hilal Taymaz-Nikerel, Juan-Carlos Sigala, Guillermo Gosset, Jochen Büchs, Alvaro R Lara

Journal: Microorganisms

PubMed ID: 38257977

Doi: 10.3390/microorganisms12010150

Products & Services: Molecular Biology Reagents

Identification and application of an exocarp-preferential promoter for genetic engineering of tomato fruit

Authors: Xue-Ming Ruan, Xiangyu Xiong, Jian-Feng Li

Journal: Hortic Res

PubMed ID: 38544552

Doi: 10.1093/hr/uhae035

Products & Services: Catalog Antibody

Cluster-Enhanced Nanopore Sensing of Ovarian Cancer Marker Peptides in Urine

Authors: Thomas W Rockett, Mohammed Almahyawi, Madhav L Ghimire, Aashna Jonnalagadda, Victoria Tagliaferro, Sarah J Seashols-Williams, Massimo F Bertino, Gregory A Caputo, Joseph E Reiner

Journal: ACS Sens

PubMed ID: 38286995

Doi: 10.1021/acssensors.3c02207

Products & Services: Catalog Peptides

Combined biolistic and cell penetrating peptide delivery for the development of scalable intradermal DNA vaccines

Authors: Roizza Beth So, Gang Li, Victoria Brentville, Janet M Daly, James E Dixon

Journal: J Control Release

PubMed ID: 38244841

Doi: 10.1016/j.jconrel.2024.01.031

Products & Services: Proteins, Expression, Isolation and Analysis

Therapeutic effect of long-acting FGF21 with controlled site-specific modification on nonalcoholic steatohepatitis

Authors: Jianying Qi, Zhimou Guo, Shenglong Zhu, Xuan Jiang, Yuanyuan Wu, Yingli Chen, Fei Hu, Jingjing Xiong, YunZhou Wu, Xianlong Ye, Xinmiao Liang

Journal: Int J Biol Macromol

PubMed ID: 38290625

Doi: 10.1016/j.ijbiomac.2024.129797

Products & Services: Molecular Biology Reagents

Oleuropein-driven reprogramming of the myeloid cell compartment to sensitise tumours to PD-1/PD-L1 blockade strategies

Authors: Ester Blanco, Noelia Silva-Pilipich, Ana Bocanegra, Luisa Chocarro, Antonio Procopio, Karina Ausín, Joaquín Fernandez-Irigoyen, Leticia Fernández, Nerea Razquin, Ana Igea, Maider Garnica, Miriam Echaide, Hugo Arasanz, Ruth Vera, David Escors, Cristian Smerdou, Grazyna Kochan

Journal: Br J Cancer

PubMed ID: 38195888

Doi: 10.1038/s41416-023-02561-y

Products & Services: Molecular Biology Reagents