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MiR-326 sponges TET2 triggering imbalance of Th17/Treg differentiation to exacerbate pyroptosis of hepatocytes in concanavalin A-induced autoimmune hepatitis

Authors: Genglin Zhang, Sensen Wu, Guangtao Xia

Journal: Hepatology

PubMed ID: 38043702

Doi: 10.1016/j.aohep.2023.101183

Products & Services: Codon Optimization

Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4-induced brain pathology

Authors: Brendan Miller, Su-Jeong Kim, Kevin Cao, Hemal H Mehta, Neehar Thumaty, Hiroshi Kumagai, Tomomitsu Iida, Cassandra McGill, Christian J Pike, Kamila Nurmakova, Zachary A Levine, Patrick M Sullivan, Kelvin Yen, Nilüfer Ertekin-Taner, Gil Atzmon, Nir Barzilai, Pinchas Cohen

Journal: Cell

PubMed ID: 38520065

Doi: 10.1111/acel.14153

Products & Services: Gene Synthesis

A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins

Authors: Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters

Journal: Nature

PubMed ID: 38509117

Doi: 10.1038/s41467-024-46644-7

Products & Services: Plasmid DNA Preparation

Development of a colloidal gold immunochromatographic strip for rapid detection of avian coronavirus infectious bronchitis virus

Authors: Chang-Run Zhao, Li-Ting Lin, Jin-Wen Tang, Yu Zhang, Wen Zhang, Ji-Ming Chen, Ping Wei, Teng Huang, Tian-Chao Wei, Mei-Lan Mo

Journal: Poult Sci

PubMed ID: 38574460

Doi: 10.1016/j.psj.2024.103648.

Products & Services: Proteins, Expression, Isolation and Analysis

A common protein C inhibitor exosite partially controls the heparin induced activation and inhibition of serine proteases

Authors: Urfi Siddiqui, Abdul Burhan Khan, Tahif Ahmad, Ahmed Abdur Rehman, Mohamad Aman Jairajpuri

Journal: Int J Biol Macromol

PubMed ID: 38521329

Doi: 10.1016/j.ijbiomac.2024.131065

Products & Services: PCR Cloning and Subcloning

OsWRKY78 regulates panicle exsertion via gibberellin signaling pathway in rice

Authors: Enyang Mei, Mingliang He, Min Xu, Jiaqi Tang, Jiali Liu, Yingxiang Liu, Zhipeng Hong, Xiufeng Li, Zhenyu Wang, Qingjie Guan, Xiaojie Tian, Qingyun Bu

Journal: J Integr Plant Biol

PubMed ID: 38470298

Doi: 10.1111/jipb.13636

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis for RAD18 regulation by MAGEA4 and its implications for RING ubiquitin ligase binding by MAGE family proteins

Authors: Simonne Griffith-Jones, Lucía Álvarez, Urbi Mukhopadhyay, Sarah Gharbi, Mandy Rettel, Michael Adams, Janosch Hennig, Sagar Bhogaraju

Journal: EMBO J

PubMed ID: 38448672

Doi: 10.1038/s44318-024-00058-9

Products & Services: Catalog Peptides

Saikosaponin d protects pancreatic acinar cells against cerulein-induced pyroptosis through alleviating mitochondrial damage and inhibiting cGAS-STING pathway

Authors: Hui Chen, Xirong Lu, Beiqi Xu, Gang Cheng, Yuyi Li, Dan Xie