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N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting

Authors: Thomas E Mulroney, Tuija Pöyry, Juan Carlos Yam-Puc, Maria Rust, Robert F Harvey, Lajos Kalmar, Emily Horner, Lucy Booth, Alexander P Ferreira, Mark Stoneley, Ritwick Sawarkar, Alexander J Mentzer, Kathryn S Lilley, C Mark Smales, Tobias von der Haar, Lance Turtle, Susanna Dunachie, Paul Klenerman, James E D Thaventhiran, Anne E Willis

Journal: Nature

PubMed ID: 38057663

Doi: 10.1038/s41586-023-06800-3

Products & Services: PCR Cloning and Subcloning

Diverse array of neutralizing antibodies elicited upon Spike Ferritin Nanoparticle vaccination in rhesus macaques

Authors: Rajeshwer S Sankhala , Kerri G Lal , Jaime L Jensen , Vincent Dussupt , Letzibeth Mendez-Rivera , Hongjun Bai , Lindsay Wieczorek , Sandra V Mayer , Michelle Zemil , Danielle A Wagner , Samantha M Townsley , Agnes Hajduczki , William C Chang , Wei-Hung Chen , Gina C Donofrio , Ningbo Jian , Hannah A D King , Cynthia G Lorang , Elizabeth J Martinez , Phyllis A Rees , Caroline E Peterson , Fabian Schmidt , Tricia J Hart , Debra K Duso , Lawrence W Kummer , Sean P Casey , Jazmean K Williams , Shruthi Kannan , Bonnie M Slike , Lauren Smith , Isabella Swafford , Paul V Thomas , Ursula Tran , Jeffrey R Currier , Diane L Bolton , Edgar Davidson , Benjamin J Doranz , Theodora Hatziioannou , Paul D Bieniasz , Dominic Paquin-Proulx , William W Reiley , Morgane Rolland , Nancy J Sullivan , Sandhya Vasan , Natalie D Collins , Kayvon Modjarrad , Gregory D Gromowski , Victoria R Polonis , Nelson L Michael , Shelly J Krebs , M Gordon Joyce

Journal: Nat Commun

PubMed ID: 38172512

Doi: 10.1038/s41467-023-44265-0.

Products & Services: Antibody Modification and Purification Services

Therapeutic vaccination with lentiviral vector in HBV-persistent mice and two inactive HBsAg carriers

Authors: Yumeng Zhang, Maryline Bourgine , Yanmin Wan, Jieyu Song, Zongying Li, Yiqi Yu, Wangfang Jiang, Mingzhe Zhou, Cuiyuan Guo, Didier Santucci, Xiao Liang, Christian Brechot, Wenhong Zhang, Pierre Charneau, Hong Wu, Chao Qiu

Journal: Hepatology

PubMed ID: 37827470

Doi: 10.1016/j.jhep.2023.09.019

Products & Services: Peptide Synthesis

Predicting multiple conformations via sequence clustering and AlphaFold2

Authors: Hannah K Wayment-Steele, Adedolapo Ojoawo, Renee Otten, Julia M Apitz, Warintra Pitsawong, Marc Hömberger, Sergey Ovchinnikov, Lucy Colwell, Dorothee Kern

Journal: Nature

PubMed ID: 37956700

Doi: 10.1038/s41586-023-06832-9

Products & Services: Custom Vector Construction

A new antibiotic traps lipopolysaccharide in its intermembrane transporter

Authors: Karanbir S Pahil, Morgan S A Gilman, Vadim Baidin, Thomas Clairfeuille, Patrizio Mattei, Christoph Bieniossek, Fabian Dey, Dieter Muri, Remo Baettig, Michael Lobritz, Kenneth Bradley, Andrew C Kruse 4, Daniel Kahne 5

Journal: Nature

PubMed ID: 38172635

Doi: 10.1038/s41586-023-06799-7

Products & Services: Peptide Synthesis

Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution

Authors: Jason Z. Zhang, William H. Nguyen, Nathan Greenwood, John C. Rose, Shao-En Ong, Dustin J. Maly & David Baker

Journal: Nature Biotechnol

PubMed ID: 38228150

Doi: 10.1038/s41587-023-02107-w

Products & Services: Plasmid DNA Preparation

Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis

Authors: Xiao-Yu Ji, Yu-Xin Guo, Li-Bin Wang, Wen-Cheng Wu, Jia-Qi Wang, Jin He, Rui Gao, Javad Rasouli, Meng-Yuan Gao, Zhen-Hai Wang, Dan Xiao, Wei-Feng Zhang, Bogoljub Ciric, Yuan Zhang, Xing Li

Journal: J Neuroinflammation

PubMed ID: 38246987

Doi: 10.1186/s12974-024-03019-5

Products & Services: Catalog Peptides

A CRISPR-Cas12a-based electrochemical biosensor for the detection of microphthalmia-associated transcription factor

Authors: Qisheng Luo, Chunyuan Zhang, Xiandong Deng, Dongyuan Liu, Xingchen Pan, Yuanxun Gong, Qianli Tang, Kai Zhang, Xianjiu Liao

Journal: Mikrochim Acta

PubMed ID: 38170285

Doi: 10.1007/s00604-023-06164-5

Products & Services: Custom DNA/RNA Oligos

Fragment-based screening targeting an open form of the SARS-CoV-2 main protease binding pocket

Authors: Chia Ying Huang, Alexander Metz, Roland Lange, Nadia Artico, Céline Potot, Julien Hazemann, Manon Müller, Marina Dos Santos, Alain Chambovey, Daniel Ritz, Deniz Eris, Solange Meyer, Geoffroy Bourquin, May Sharpe, Aengus Mac Sweeney

Journal: Acta Crystallogr D Struct Biol

PubMed ID: 38289714

Doi: 10.1107/S2059798324000329

Products & Services: Proteins, Expression, Isolation and Analysis

Beta-1,3-Glucan-Binding Protein Inhibits Dengue and ZIKA Virus Replication

Authors: Xiaoxue Xie, Di Wang, Bo Li, Guorui Liang, Xiaoli Chen, Dan Xing, Teng Zhao, Xinyu Zhou, Chunxiao Li

Journal: Biomedicines

PubMed ID: 38255195

Doi: 10.3390/biomedicines12010088

Products & Services: DNA Sequencing