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页码: 114/5114 每页显示数量

HTRA1 disaggregates α-synuclein amyloid fibrils and converts them into non-toxic and seeding incompetent species

Authors: Sheng Chen, Anuradhika Puri, Braxton Bell, Joseph Fritsche, Hector H Palacios, Maurie Balch, Macy L Sprunger, Matthew K Howard, Jeremy J Ryan, Jessica N Haines, Gary J Patti, Albert A Davis, Meredith E Jackrel

Journal: Nat Commun

PubMed ID: 38499535

Doi: 10.1038/s41467-024-46538-8

Products & Services: Molecular Biology Reagents

Endothelial β-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9

Authors: Zhenfeng Chen, Bingqi Lin, Xiaodan Yao, Jie Weng, Jinlian Liu, Qi He, Ke Song, Chuyu Zhou, Zirui Zuo, Xiaoxia Huang, Zhuanhua Liu, Qiaobing Huang, Qiulin Xu, Xiaohua Guo

Journal: Cell Commun Signal

PubMed ID: 38491522

Doi: 10.1186/s12964-024-01566-1

Products & Services: Recombinant Proteins

Reactive Oxygen Species-Responsive Nanoparticles Toward Extracellular Matrix Normalization for Pancreatic Fibrosis Regression

Authors: Liang Qi, Bo-Wen Duan, Hui Wang, Yan-Jun Liu, Han Han, Meng-Meng Han, Lei Xing, Hu-Lin Jiang, Stephen J Pandol, Ling Li

Journal: Adv Sci (Weinh)

PubMed ID: 38483920

Doi: 10.1002/advs.202401254

Products & Services: Catalog Antibody

Highly sensitive spatial transcriptomics using FISHnCHIPs of multiple co-expressed genes

Authors: Xinrui Zhou , Wan Yi Seow, Norbert Ha, Teh How Cheng, Lingfan Jiang, Jeeranan Boonruangkan, Jolene Jie Lin Goh, Shyam Prabhakar, Nigel Chou, Kok Hao Chen Affiliations expand

Journal: Nat Commun

PubMed ID: 38491027

Doi: s41467-024-46669-y

Products & Services: Gene Synthesis

Novel Fragment Inhibitors of PYCR1 from Docking-Guided X-ray Crystallography

Authors: Kaylen R Meeks, Juan Ji , Mykola V Protopopov , Olga O Tarkhanova , Yurii S Moroz , John J Tanner

Journal: J Chem Inf Model

PubMed ID: 38411104

Doi: 10.1021/acs.jcim.3c01879

Products & Services: Molecular Biology Reagents

Structural investigation of pathogenic RFC1 AAGGG pentanucleotide repeats reveals a role of G-quadruplex in dysregulated gene expression in CANVAS

Authors: Yang Wang, Junyan Wang, Zhenzhen Yan, Jianing Hou, Liqi Wan, Yingquan Yang, Yu Liu, Jie Yi, Pei Guo, Da Han

Journal: Nucleic Acids Res

PubMed ID: 38266156

Doi: 10.1093/nar/gkae032

Products & Services: Custom Vector Construction

Exploring functional genes' correlation with ()-equol concentration and new daidzein racemase identification

Authors: Yun-Fei Hu, Shu Luo, Sheng-Qi Wang, Ke-Xin Chen, Wei-Xuan Zhong, Bai-Yuan Li, Lin-Yan Cao, Hua-Hai Chen, Ye-Shi Yin

Journal: Appl Environ Microbiol

PubMed ID: 38501861

Doi: 10.1128/aem.00007-24

Products & Services: Molecular Biology Reagents

Morusin Alleviates Aortic Valve Calcification by Inhibiting Valve Interstitial Cell Senescence Through Ccnd1/Trim25/Nrf2 Axis

Authors: Zongtao Liu, Kan Wang, Chen Jiang, Yuqi Chen, Fayuan Liu, Minghui Xie, Wai Yen Yim, Dingyi Yao, Xingyu Qian, Shiqi Chen, Jiawei Shi, Kang Xu, Yixuan Wang, Nianguo Dong

Journal: Adv Sci (Weinh)

PubMed ID: 38502885

Doi: 10.1002/advs.202307319

Products & Services: Gene Synthesis

Association mechanism between Arabidopsis immune coreceptor BAK1 and Pseudomonas syringae effector HopF2

Authors: Rui Han, Tongtong Zhu, Lili Zhou, Meiqing Chen, Dongli Wang, Junfeng Liu

Journal: Biochem Biophys Res Commun

PubMed ID: 38579538

Doi: 10.1016/j.bbrc.2024.149871

Products & Services: Proteins, Expression, Isolation and Analysis

23-Hydroxybetulinic acid attenuates 5-fluorouracil resistance of colorectal cancer by modulating M2 macrophage polarization via STAT6 signaling

Authors: Zeping Fan, Yaru Cui, Lanying Chen, Peng Liu, Wenbin Duan