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Pax6 mediates ß-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells.

Authors: Q Gan, A Lee, R Suzuki, T Yamagami, A Stokes, Bao Chau Nguyen, David Pleasure, Junjiang Wang, Hong-Wu Chen, Chengji J. Zhou.

Journal: Stem Cells.

The N-Terminal Phosphodegron Targets Taz/Wwtr1 Protein For ScfΒ-Trcp-Dependent Degradation In Response To Phosphatidylinositol 3-Kinase Inhibition.

Authors: Wei Huang, Xianbo Lv, Chenying Liu, Zhengyu Zha, Heng Zhang, Ying Jiang, Yue Xiong, Qun-Ying Lei, and Kun-Liang Guan.

Journal: J Biol Chem. 287(31):26245 - 26253

PubMed ID: 22692215

Targeted polyubiquitylation of RASSF1C by the Mule and SCFbeta-TrCP ligases in response to DNA damage.

Authors: Xin Zhou, Ting?Ting Li, Xu Feng, Esther Hsiang, Yue Xiong, Kun?Liang Guan and Qun?Ying Lei.

Journal: Biochem J. 441(1):227-36

PubMed ID: 21910689

PP1 Cooperates with ASPP2 to Dephosphorylate and Activate TAZ.

Authors: Chen-Ying Liu, Xianbo Lv, Tingting Li, Yanping Xu, Xin Zhou, Shimin Zhao, Yue Xiong, Qun-Ying Lei, and Kun-Liang Guan.

Journal: J Biol Chem. 286(7):5558 - 5566

PubMed ID: 21189257

The Hippo Tumor Pathway Promotes TAZ Degradation by Phosphorylating a Phosphodegron and Recruiting the SCF^β-TrCP E3 Ligase.

Authors: Chen-Ying Liu, Zheng-Yu Zha, Xin Zhou, Heng Zhang, Wei Huang, Di Zhao, Tingting Li, Siew Wee Chan, Chun Jye Lim, Wanjin Hong, Shimin Zhao, Yue Xiong, Qun-Ying Lei, and Kun-Liang Guan.

Journal: J Biol Chem. 285(48):37159 - 37169

PubMed ID: 20858893

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.

Authors: Heng Zhang, Chen-Ying Liu, Zheng-Yu Zha, Bin Zhao, Jun Yao, Shimin Zhao, Yue Xiong, Qun-Ying Lei, and Kun-Liang Guan.

Journal: J Biol Chem.

PubMed ID: 19324877

TAZ promotes cell proliferation and EMT and is inhibited by the Hippo pathway.

Authors: Qunying Lei, Heng Zhang, Bin Zhao, Zheng-Yu Zha, Feng Bai, Xin-Hai Pei, Shimin Zhao, Yue Xiong, and Kun-Liang Guan.

Journal: Mol Cell Biol. 28(7):2426 - 2436

PubMed ID: 18227151