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Development of a C3 humanized rat as a new model for evaluating novel C3 inhibitors

Authors: Jin Chen, Lingjun Zhang, Maojing Yang, Elizabeth D Hughes, Zach Freeman, Thomas L Saunders, Feng Lin

Journal: J Innate Immun

PubMed ID: 38035563

Doi: 10.1159/000534963

Products & Services: Plasmid DNA Preparation

Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants

Authors: Shudan Tan, Jinghua Zhao, Xue Hu, Yufeng Li, Zihan Wu, Guoliang Lu, Zhaoli Yu, Binhe Du, Yan Liu, Li Li, Yuchen Chen, Ye Li, Yanfeng Yao, Xiaoyu Zhang, Juhong Rao, Ge Gao, Yun Peng, Hang Liu, Zhiming Yuan, Jia Liu, Qianran Wang, Hengrui Hu, Xiaobo Gao, Hui Zhou, Hang Yu, Yingjie Xu, Wei Yu, Lin Feng, Manli Wang, Chao Shan, Jing Lu, Jinzhong Lin

Journal: Sci Bull (Beijing)

PubMed ID: 37993332

Doi: 10.1016/j.scib.2023.11.024

Products & Services: Plasmids for SARS-CoV-2 Detection and Research

Enhancement of adeno-associated virus serotype 6 transduction into T cells with cell-penetrating peptides

Authors: Pablo D Moço, Shantoshini Dash, Amine A Kamen

Journal: J Gene Med

PubMed ID: 37957034

Doi: 10.1002/jgm.3627

Products & Services: Catalog Peptides

Self−Assembling Nanovaccine Fused with Flagellin Enhances Protective Effect against Foot−and−Mouth Disease Virus

Authors: Chenchen Pei , Hu Dong , Zhidong Teng , Sumin Wei , Yun Zhang , Shuanghui Yin , Jianli Tang , Shiqi Sun and Huichen Guo

Journal: Vaccines

Doi: 10.3390/vaccines11111675

Products & Services: Gene Synthesis

Multiple highly expressed phosphoenolpyruvate carboxylase genes have divergent enzyme kinetic properties in two C4 grasses

Authors: Robert J DiMario, Ashley N Kophs, Anthony J A Apalla, James N Schnable, Asaph B Cousins

Journal: Ann Bot

PubMed ID: 37675505

Doi: 10.1093/aob/mcad116

Products & Services: Proteins, Expression, Isolation and Analysis

The yeast prion protein Sup35 initiates α-synuclein pathology in mouse models of Parkinson's disease

Authors: Lanxia Meng, Congcong Liu, Yiming Li, Guiqin Chen, Min Xiong, Ting Yu, Lina Pan, Xingyu Zhang, Lingyan Zhou, Tao Guo, Xin Yuan, Chaoyang Liu, Zhaohui Zhang, Zhentao Zhang

Journal: Sci Adv

PubMed ID: 37910610

Doi: 10.1126/sciadv.adj1092

Products & Services: Peptide Synthesis

Depletion of L-Methionine in Foods with an Engineered Thermophilic Methionine γ-lyase Efficiently Inhibits Tumor Growth

Authors: Yangming Hu, Yan Liu, Jiulin Zhang, Zhijing Zhou, Jiaxue Wang, Hongyang Chen, Meina Huang, Han Hu, Zongjie Dai, Kaizhi Jia

Journal: J Agric Food Chem

PubMed ID: 37909421

Doi: 10.1021/acs.jafc.3c05293

Products & Services: Proteins, Expression, Isolation and Analysis

A novel stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids

Authors: Jennifer M Podgorski, Joshua Podgorski, Lawrence Abad, Deborah Jacobs-Sera, Krista G Freeman, Colin Brown, Graham Hatfull, Antoni Luque, Simon J White

Journal: biorxiv

PubMed ID: 37961133

Doi: 10.1101/2023.11.03.565530

Products & Services: Proteins, Expression, Isolation and Analysis

Evaluating the stability of host-reference gene expression and simultaneously quantifying parasite burden and host immune responses in murine malaria

Authors: Daniel J Browne, Ashton M Kelly, Jamie Brady, Carla Proietti, Yomani D Sarathkumara, David J Pattinson, Denise L Doolan

Journal: Sci Rep

PubMed ID: 38030676

Doi: 10.1038/s41598-023-48066-9

Products & Services: Plasmid DNA Preparation

Enhanced C-To-T and A-To-G Base Editing in Mitochondrial DNA with Engineered DdCBE and TALED

Authors: Yinghui Wei, Ming Jin, Shuhong Huang, Fangyao Yao, Ningxin Ren, Kun Xu, Shangpu Li, Pengfei Gao, Yingsi Zhou, Yulin Chen, Hui Yang, Wen Li, Chunlong Xu, Meiling Zhang, Xiaolong Wang

Journal: Adv Sci (Weinh)

PubMed ID: 37984866

Doi: 10.1002/advs.202304113

Products & Services: Codon Optimization