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Sub-millisecond conformational dynamics of the A adenosine receptor revealed by single-molecule FRET

Authors: Ivan Maslov, Oleksandr Volkov, Polina Khorn, Philipp Orekhov, Anastasiia Gusach, Pavel Kuzmichev, Andrey Gerasimov, Aleksandra Luginina, Quinten Coucke, Andrey Bogorodskiy, Valentin Gordeliy, Simon Wanninger, Anders Barth, Alexey Mishin, Johan Hofkens, Vadim Cherezov, Thomas Gensch, Jelle Hendrix, Valentin Borshchevskiy

Journal: Commun Biol

PubMed ID: 37012383

Doi: 10.1038/s42003-023-04727-z

Products & Services: Molecular Biology Reagents

Codon pair bias deoptimization of essential genes in infectious laryngotracheitis virus reduces protein expression

Authors: Paola K Vaz, Marzieh Armat, Carol A Hartley, Joanne M Devlin

Journal: J Gen Virol

PubMed ID: 37010948

Doi: 10.1099/jgv.0.001836

Products & Services: Molecular Biology Reagents

A triple amplification strategy using GR-5 DNAzyme as a signal medium for ultrasensitive detection of trace Pb based on CRISPR/Cas12a empowered electrochemical biosensor

Authors: Yuanyuan Yue, Songtao Wang, Qiang Jin, Nan An, Lina Wu, He Huang

Journal: Anal Chim Acta

PubMed ID: 37225346

Doi: 10.1016/j.aca.2023.341241

Products & Services: Proteins, Expression, Isolation and Analysis

SLFN5-mediated chromatin dynamics sculpt higherorder DNA repair topology

Authors: Jinzhou Huang, Chenming Wu, Jake A Kloeber, Huanyao Gao, Ming Gao, Qian Zhu, Yiming Chang, Fei Zhao, Guijie Guo, Kuntian Luo, Haiming Dai, Sijia Liu, Qiru Huang, Wootae Kim, Qin Zhou, Shouhai Zhu, Zheming Wu, Xinyi Tu, Ping Yin, Min Deng, Liewei Wang, Jian Yuan, Zhenkun Lou

Journal: molecular cell

PubMed ID: 36854302

Doi: 10.1016/j.molcel.2023.02.004

Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)

Modulatory role of copper on hIAPP aggregation and toxicity in presence of insulin

Authors: Dipanwita Roy, Narayan Chandra Maity, Sourav Kumar, Anupam Maity, Bhisma N Ratha, Ranjit Biswas, Nakul Chandra Maiti, Atin Kumar Mandal, Anirban Bhunia

Journal: Int J Biol Macromol

PubMed ID: 37088193

Doi: 10.1016/j.ijbiomac.2023.124470

Products & Services: Peptide Synthesis

Computational design and molecular dynamics simulations suggest the mode of substrate binding in ceramide synthases

Authors: Iris D Zelnik, Beatriz Mestre, Jonathan J Weinstein, Tamir Dingjan, Stav Izrailov, Shifra Ben-Dor, Sarel J Fleishman, Anthony H Futerman

Journal: Nat Commun

PubMed ID: 37087500

Doi: 10.1038/s41467-023-38047-x

Products & Services: Proteins, Expression, Isolation and Analysis

A Recombinant Chimeric Cedar Virus-Based Surrogate Neutralization Assay Platform for Pathogenic Henipaviruses

Authors: Moushimi Amaya, Randy Yin, Lianying Yan, Viktoriya Borisevich, Bishwo N Adhikari, Andrew Bennett, Francisco Malagon, Regina Z Cer, Kimberly A Bishop-Lilly, Antony S Dimitrov, Robert W Cross, Thomas W Geisbert, Christopher C Broder

Journal: Viruses

PubMed ID: 37243163

Doi: 10.3390/v15051077

Products & Services: Molecular Biology Reagents

H, N, C backbone and Cβ resonance assignments for UBQLN1 UBA and UBAA domains

Authors: Gwen R Buel, Xiang Chen, Olumide Kayode, Anthony Cruz, Kylie J Walters

Journal: Biomol NMR Assign

PubMed ID: 37022617

Doi: 10.1007/s12104-023-10127-5

Products & Services: Custom Vector Construction

Enhanced Degradation of Mutant -Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection

Authors: Allison S Vanecek, Jelena Mojsilovic-Petrovic, Robert G Kalb, Jetze J Tepe