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MCT4 and CD147 colocalize with MMP14 in invadopodia and support matrix degradation and invasion by breast cancer cells

Authors: Signe Meng, Ester E Sørensen, Muthulakshmi Ponniah, Jeppe Thorlacius-Ussing, Roxane Crouigneau, Tanja Larsen, Magnus T Borre, Nicholas Willumsen, Mette Flinck, Stine F Pedersen

Journal: J Cell Sci

PubMed ID: 38661040

Doi: 10.1242/jcs.261608

Products & Services: Proteins, Expression, Isolation and Analysis

mARC1 in MASLD: Modulation of lipid accumulation in human hepatocytes and adipocytes

Authors: Amanda K Jones, Besnik Bajrami, Morgan K Campbell, Abdullah Mesut Erzurumluoglu, Qiusha Guo, Hongxing Chen, Xiaomei Zhang, Svetlana Zeveleva, David Kvaskoff, Andreas-David Brunner, Stefanie Muller, Vasudha Gathey, Rajvee M Dave, James W Tanner, Sophia Rixen, Michel A Struwe, Kathryn Phoenix, Kaitlyn J Klumph, Heather Robinson, Daniel Veyel, Annkatrin Muller, Boris Noyvert, Boris Alexander Bartholdy, Agnes A Steixner-Kumar, Jan Stutzki, Dmitriy Drichel, Steffen Omland, Ryan Sheehan, Jon Hill, Tom Bretschneider, Dirk Gottschling, Axel J Scheidig, Bernd Clement, Martin Giera, Zhihao Ding, John Broadwater, Curtis R Warren

Journal: Hepatol Commun

PubMed ID: 38619429

Doi: 10.1097/HC9.0000000000000365

Products & Services: Molecular Biology Reagents

Characterization of genital chlamydia trachomatis infection among women attending infertility and gynecology clinics in Hunan, China

Authors: Qianting Zhou, Jiayan Li, Lipei Luo, Shuling Min, Li Wang, Lixiu Peng, Yinglan Hou, Ping He, Song He, Shixing Tang, Hongliang Chen

Journal: BMC Infect Dis

PubMed ID: 38622501

Doi: 10.1186/s12879-024-09254-8

Products & Services: Proteins, Expression, Isolation and Analysis

Structural basis for human Cav3.2 inhibition by selective antagonists

Authors: Jian Huang, Xiao Fan, Xueqin Jin, Chen Lyu, Qinmeng Guo, Tao Liu, Jiaofeng Chen, Amaël Davakan, Philippe Lory, Nieng Yan

Journal: Cell Research

PubMed ID: 38605177

Doi: 10.1038/s41422-024-00959-8

Products & Services: Peptide Synthesis

Comparison of antibody-based immunotherapeutics for malignant hematological disease in an experimental murine model

Authors: Karin Frebel, Jörn C Albring, Anika Wohlgemuth, Christian Schwöppe, Stephan Hailfinger, Georg Lenz, Matthias Stelljes

Journal: Blood

PubMed ID: 38197968

Doi: 10.1182/bloodadvances.2023011647

Products & Services: Molecular Biology Reagents

Somatic and intergenerational G4C2 hexanucleotide repeat instability in a human C9orf72 knock-in mouse model

Authors: Nada Kojak, Junko Kuno, Kristina E Fittipaldi, Ambereen Khan, David Wenger, Michael Glasser, Roberto A Donnianni, Yajun Tang, Jade Zhang, Katie Huling, Roxanne Ally, Alejandro O Mujica, Terrence Turner, Gina Magardino, Pei Yi Huang, Sze Yen Kerk, Gustavo Droguett, Marine Prissette, Jose Rojas, Teodoro Gomez, Anthony Gagliardi, Charleen Hunt, Jeremy S Rabinowitz, Guochun Gong, William Poueymirou, Eric Chiao, Brian Zambrowicz, Chia-Jen Siao, Daisuke Kajimura

Journal: Nucleic Acids Res

PubMed ID: 38597682

Doi: 10.1093/nar/gkae250

Products & Services: PCR Cloning and Subcloning

A hemoprotein with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria

Authors: Nicolas Grosjean, Estella F Yee, Desigan Kumaran, Kriti Chopra, Macon Abernathy, Sandeep Biswas, James Byrnes, Dale F Kreitler, Jan-Fang Cheng, Agnidipta Ghosh, Steven C Almo, Masakazu Iwai, Krishna K Niyogi, Himadri B Pakrasi, Ritimukta Sarangi, Hubertus van Dam, Lin Yang, Ian K Blaby, Crysten E Blaby-Haas

Journal: Nature Communications

PubMed ID: 38609367

Doi: 10.1038/s41467-024-47486-z

Products & Services: Proteins, Expression, Isolation and Analysis

A folate inhibitor exploits metabolic differences in Pseudomonas aeruginosa for narrow-spectrum targeting

Authors: Connor Chain, Joseph P Sheehan, Xincheng Xu, Soodabeh Ghaffari, Aneesh Godbole, Hahn Kim, Joel S Freundlich, Joshua D Rabinowitz, Zemer Gitai

Journal: Nature Microbiology

PubMed ID: 38594311

Doi: 10.1038/s41564-024-01665-2

Products & Services: Antibody Modification and Purification Services

Human inherited PD-L1 deficiency is clinically and immunologically less severe than PD-1 deficiency

Authors: Matthew B Johnson, Masato Ogishi, Clara Domingo-Vila, Elisa De Franco, Matthew N Wakeling, Zineb Imane, Brittany Resnick, Evangelia Williams, Rui Pedro Galão, Richard Caswell, James Russ-Silsby, Yoann Seeleuthner , Darawan Rinchai, Iris Fagniez, Basilin Benson, Matthew J Dufort, Cate Speake , Megan E Smithmyer, Michelle Hudson, Rebecca Dobbs; EXE-T1D consortium; Zoe Quandt, Andrew T Hattersley ,Peng Zhang, Stephanie Boisson-Dupuis , Mark S Anderson, Jean-Laurent Casanova, Timothy I Tree, Richard A Oram

Journal: Journal Of Experimental Medicine

PubMed ID: 38634869

Doi: 10.1084/jem.20231704

Products & Services: Catalog Antibody

Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade

Authors: Hao Nie, Pratima Saini, Taito Miyamoto, Liping Liao, Rafal J Zielinski, Heng Liu, Wei Zhou, Chen Wang, Brennah Murphy, Martina Towers, Tyler Yang, Yuan Qi, Toshitha Kannan, Andrew Kossenkov, Hiroaki Tateno, Daniel T Claiborne, Nan Zhang, Mohamed Abdel-Mohsen, Rugang Zhang

Journal: Nature Communications

PubMed ID: 38565883

Doi: 10.1038/s41467-024-47069-y

Products & Services: Gene Synthesis