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Enabling high-throughput enzyme discovery and engineering with a low-cost, robot-assisted pipeline

Authors: Brenna Norton-Baker, Mackenzie C R Denton, Natasha P Murphy, Benjamin Fram, Samuel Lim, Erika Erickson, Nicholas P Gauthier, Gregg T Beckham

Journal: Sci Rep

PubMed ID: 38914665

Doi: 10.1038/s41598-024-64938-0

Products & Services: Proteins, Expression, Isolation and Analysis

Host Poly(A) Polymerases PAPD5 and PAPD7 Provide Two Layers of Protection That Ensure the Integrity and Stability of Hepatitis B Virus RNA

Authors: Fei Liu, Amy C H Lee, Fang Guo, Andrew S Kondratowicz, Holly M Micolochick Steuer, Angela Miller, Lauren D Bailey, Xiaohe Wang, Shuai Chen, Steven G Kultgen, Andrea Cuconati, Andrew G Cole, Dimitar Gotchev, Bruce D Dorsey, Rene Rijnbrand, Angela M Lam, Michael J Sofia, Min Gao

Journal: J Virol

PubMed ID: 34191584

Doi: 10.1128/JVI.00574-21

Products & Services: Gene Synthesis

Rapid and multiplex preparation of engineered Mycobacterium smegmatis porin A (MspA) nanopores for single molecule sensing and sequencing

Authors: Shuanghong Yan , Liying Wang , Xiaoyu Du , Shanyu Zhang , Sha Wang , Jiao Cao , Jinyue Zhang , Wendong Jia , Yuqin Wang , Panke Zhang , Hong-Yuan Chen , Shuo Huang

Journal: Chem Sci

PubMed ID: 34349904

Doi: 10.1039/D1SC01399H

Products & Services: Custom DNA/RNA Oligos Proteins, Expression, Isolation and Analysis

Exploring the Lower Limit of Individual DNA-Encoded Library Molecules in Selection

Authors: Chen Q, Cheng X, Zhang L, Li X, Chen P, Liu J, Zhang L, Wei H, Li Z, Dou D

Journal: SLAS discovery : advancing life sciences R & D

PubMed ID: 31858872

Doi: 10.1177/2472555219893949

Products & Services: Plasmid DNA Preparation

A DNA-encoded library for the identification of natural product binders that modulate poly (ADP-ribose) polymerase 1, a validated anti-cancer target

Authors: Jie Li, Yu Li, Fengping Lu, Lili Liu, Qun Ji, Ke Song, Qianqian Yin, Richard A Lerner, Guang Yang, Hongtao Xu, Peixiang Ma