Galaxy银河|澳门官网·登录入口

至今,GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次,处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果,再次证明GenScript 有能力帮助业内科学家Make research easy.

Pharmacological Effects of EGLP-1, a Novel Analog of Glucagon-Like Peptide-1, on Carbohydrate and Lipid Metabolism.

Cell. Physiol. Biochem.. 2018; 
GaoHuashan,SongZiwei,ZhaoQian,WuYou,TangShanshan,AlahdalMurad,ShenYumeng,XingYun,PanYi,LiJing,ZhangYanfeng,JinL
Products/Services Used Details Operation
Peptide Synthesis … effect on NEFA lipid metabolism. Materials and Methods. Peptide synthesis. GLP-1, exendin-4, and EGLP-1 were chemically synthesized by GenScript (Nanjing, China). Biological activities in vitro. The CG-HEK293 cell line was … Get A Quote

摘要

Abnormal glucose metabolism and lipid metabolism are two key issues in Type 1 diabetes mellitus (T1DM). Insulin can control carbohydrate metabolism adequately, but cannot regulate lipid metabolism well in patients with T1DM. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have cured type 2 diabetes mellitus in clinical trials and have improved T1DM glycemic control in preclinical studies. However, previous studies have not reported whether GLP-1 can lower the serum concentration of non-esterified fatty acids (NEFAs). In this study, we examine whether GLP-1 can affect serum NEFA levels.

关键词

EGLP-1,NEFA,PHSL,STZ-induced hyperglycemia
XML 地图